Serum IgE concentrations in hypogammaglobulinaemia and selective IgA deficiency. Studies on patients and family members
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- PMCID: PMC1713159
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Serum IgE concentrations in hypogammaglobulinaemia and selective IgA deficiency. Studies on patients and family members
D P Stites et al. Clin Exp Immunol.1972 Mar.
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Abstract
Serum IgE levels in twelve patients with adult `acquired' hypogammaglobulinaemia were markedly reduced. In addition, seventeen of fifty first degree relatives and spouses had low IgE levels. IgE levels varied among patients with selective IgA deficiency and a combined deficiency did not necessarily predispose to recurrent infections. This study suggests that the absence of IgE in certain immune deficiency states does not, by itself, decrease resistance to infection.
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