Movatterモバイル変換

[0]ホーム
URL:

Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
Thehttps:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

NIH NLM Logo
Log inShow account info
Access keysNCBI HomepageMyNCBI HomepageMain ContentMain Navigation
pubmed logo
Advanced Clipboard
User Guide

Full text links

Free PMC article
Full text links

Actions

Share

Review
.2022;10(4):385-392.
doi: 10.1007/s40136-022-00428-z. Epub 2022 Sep 21.

How to Manage Taste Disorders

Affiliations
Review

How to Manage Taste Disorders

Julien Wen Hsieh et al. Curr Otorhinolaryngol Rep.2022.

Abstract

Purpose of the review: This study aims to summarize the current state of the art of how taste disorders are clinically best managed.

Recent findings: Taste disorders are distressing for the concerned patients since eating and drinking become bothersome or impossible. Apart from nutritional problems, quality of life is impaired. Still, diagnosis and treatment of taste disorders are elusive, and general knowledge about taste and its affection is little within the population and the medical community. This review stresses the importance of accurate workup and diagnosis of taste disorders in order to offer an effective treatment. Yet unclear aspects of taste disorders are discussed, and interesting findings regarding the treatment of taste disorders are reviewed. A special focus is given to current pharmacological options on how to treat taste disorders.

Summary: Despite impressive insights into the gustatory function and molecular logic of taste receptor cells, there is currently poor clinical knowledge on the pathophysiology of taste disorders in humans. Diagnosing, measuring, and treating gustatory disorders remain restricted to a handful of specialized smell and taste centers worldwide. Despite interesting work on potential drugs treating taste disorders, many of the reported medications lack controlled and randomized trials confirming their efficacy in taste dysfunction. Future efforts need to be focused on the treatment of taste disorders.

Keywords: Depression; Dysgeusia; Retronasal; Smell; Taste; Treatment; Zinc.

© The Author(s) 2022.

PubMed Disclaimer

Conflict of interest statement

Conflict of InterestThe authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Overview of the currently accepted human taste pathway
Fig. 2
Fig. 2
Classification of taste disorders based on the clinical presentation of the symptoms
Fig. 3
Fig. 3
Overview of the current most frequently encountered differential diagnosis for taste disorders
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Hummel T, et al. Position paper on olfactory dysfunction. Rhinol Suppl. 2017;54(26):1–30. doi: 10.4193/Rhino16.248. - DOI - PubMed
    1. Zocchi D, Wennemuth G, Oka Y. The cellular mechanism for water detection in the mammalian taste system. Nat Neurosci. 2017;20(7):927–933. doi: 10.1038/nn.4575. - DOI - PubMed
    1. Deems DA, et al. Smell and taste disorders, a study of 750 patients from the University of Pennsylvania Smell and Taste Center. Arch Otolaryngol Head Neck Surg. 1991;117(5):519–528. doi: 10.1001/archotol.1991.01870170065015. - DOI - PubMed
    1. Dalton P, et al. The merging of the senses: integration of subthreshold taste and smell. Nat Neurosci. 2000;3(5):431–432. doi: 10.1038/74797. - DOI - PubMed
    1. Migneault-Bouchard C, et al. Chemosensory decrease in different forms of olfactory dysfunction. J Neurol. 2020;267(1):138–143. doi: 10.1007/s00415-019-09564-x. - DOI - PubMed

Publication types

Related information

LinkOut - more resources

Full text links
Free PMC article
Cite
Send To

NCBI Literature Resources

MeSHPMCBookshelfDisclaimer

The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited.

[8]ページ先頭
©2009-2025 Movatter.jp