Omicron subvariants escape antibodies elicited by vaccination and BA.2.2 infection

Lin Yao¹, Ka-Li Zhu¹, Xiao-Lin Jiang², Xue-Jun Wang³, Bing-Dong Zhan⁴, Hui-Xia Gao⁵, Xing-Yi Geng⁶, Li-Jun Duan³, Er-Hei Dai⁵, Mai-Juan Ma⁷

Affiliations

¹ State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, China.
² Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Jinan, China.
³ State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
⁴ Department of Laboratory Medicine, Quzhou Center for Disease Control and Prevention, Quzhou, China.
⁵ Department of Laboratory Medicine, The Fifth Hospital of Shijiazhuang, Hebei Medical University, Shijiazhuang, China.
⁶ Department of Infectious Disease Control and Prevention, Jinan Center for Disease Control and Prevention, Jinan, China.
⁷ State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, China. Electronic address: mjma@163.com.

PMID:35738299
PMCID: PMC9212811
DOI: 10.1016/S1473-3099(22)00410-8

Omicron subvariants escape antibodies elicited by vaccination and BA.2.2 infection

Lin Yao et al. Lancet Infect Dis.2022 Aug.

.2022 Aug;22(8):1116-1117.

doi: 10.1016/S1473-3099(22)00410-8. Epub 2022 Jun 20.

Authors

Lin Yao¹, Ka-Li Zhu¹, Xiao-Lin Jiang², Xue-Jun Wang³, Bing-Dong Zhan⁴, Hui-Xia Gao⁵, Xing-Yi Geng⁶, Li-Jun Duan³, Er-Hei Dai⁵, Mai-Juan Ma⁷

Affiliations

¹ State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, China.
² Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Jinan, China.
³ State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
⁴ Department of Laboratory Medicine, Quzhou Center for Disease Control and Prevention, Quzhou, China.
⁵ Department of Laboratory Medicine, The Fifth Hospital of Shijiazhuang, Hebei Medical University, Shijiazhuang, China.
⁶ Department of Infectious Disease Control and Prevention, Jinan Center for Disease Control and Prevention, Jinan, China.
⁷ State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, China. Electronic address: mjma@163.com.

PMID:35738299
PMCID: PMC9212811
DOI: 10.1016/S1473-3099(22)00410-8

No abstract available

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Conflict of interest statement

We declare no competing interests. LY, K-LZ, X-LJ, X-JW, and B-DZ contributed equally.

References

1. Arora P, Zhang L, Krüger N, et al. SARS-CoV-2 omicron sublineages show comparable cell entry but differential neutralization by therapeutic antibodies. Cell Host Microbe. 2022 doi: 10.1016/j.chom.2022.04.017. published online May 6. - DOI - PMC - PubMed
1. Evans JP, Zeng C, Qu P, et al. Neutralization of SARS-CoV-2 omicron sub-lineages BA.1, BA.1.1, and BA.2. Cell Host Microbe. 2022 doi: 10.1016/j.chom.2022.04.014. published online April 25. - DOI - PMC - PubMed
1. Chen C, Nadeau S, Yared M, et al. CoV-Spectrum: analysis of globally shared SARS-CoV-2 data to identify and characterize new variants. Bioinformatics. 2021;38:1735–1737. - PMC - PubMed
1. Macchia A, Ferrante D, Bouzas MB, et al. Immunogenicity induced by the use of alternative vaccine platforms to deal with vaccine shortages in a low- to middle-income country: results of two randomized clinical trials. Lancet Reg Health Am. 2022;9 - PMC - PubMed
1. Yu X, Wei D, Xu W, et al. Neutralizing activity of BBIBP-CorV vaccine-elicited sera against beta, delta and other SARS-CoV-2 variants of concern. Nat Commun. 2022;13 - PMC - PubMed

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Omicron subvariants escape antibodies elicited by vaccination and BA.2.2 infection

Affiliations

Omicron subvariants escape antibodies elicited by vaccination and BA.2.2 infection

Authors

Affiliations

Conflict of interest statement

References

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