Nifedipine in patients with Raynaud's syndrome--effects on radial artery blood flow
- PMID:3450524
- DOI: 10.1093/eurheartj/8.suppl_k.83
Nifedipine in patients with Raynaud's syndrome--effects on radial artery blood flow
Abstract
The acute effect of nifedipine on hand blood flow of 20 patients with Raynaud's phenomenon, treated in a double-blind, crossover study, is reported. Radial artery blood flow was found to correlate with the reciprocal of the pulsatility index. This simple Doppler technique gave an instantaneous record of the effect of cooling on hand blood flow. In patients with Raynaud's phenomenon, nifedipine prevents the reduction of hand blood flow that is induced by cooling in untreated patients.
Similar articles
- Nifedipine in primary Raynaud's phenomenon and in scleroderma: oral versus sublingual hemodynamic effects.Wollersheim H, Thien T, van 't Laar A.Wollersheim H, et al.J Clin Pharmacol. 1987 Nov;27(11):907-13. doi: 10.1002/j.1552-4604.1987.tb05587.x.J Clin Pharmacol. 1987.PMID:3429697Clinical Trial.
- Comparison of intravenous infusions of iloprost and oral nifedipine in treatment of Raynaud's phenomenon in patients with systemic sclerosis: a double blind randomised study.Rademaker M, Cooke ED, Almond NE, Beacham JA, Smith RE, Mant TG, Kirby JD.Rademaker M, et al.BMJ. 1989 Mar 4;298(6673):561-4. doi: 10.1136/bmj.298.6673.561.BMJ. 1989.PMID:2467711Free PMC article.Clinical Trial.
- Digital and radial artery blood flow in patients with Raynaud's phenomenon in response to nifedipine.Morgan RH, Psaila JV, Davies WT, Carolan G, Woodcock JP.Morgan RH, et al.Eur J Vasc Surg. 1987 Dec;1(6):403-8. doi: 10.1016/s0950-821x(87)80034-8.Eur J Vasc Surg. 1987.PMID:3503035
- Raynaud's phenomenon: pathophysiologic features and treatment with calcium-channel blockers.Smith CR, Rodeheffer RJ.Smith CR, et al.Am J Cardiol. 1985 Jan 25;55(3):154B-157B. doi: 10.1016/0002-9149(85)90625-3.Am J Cardiol. 1985.PMID:3881908Review.
- Use of nifedipine in hypertension and Raynaud's phenomenon.Kiowski W, Erne P, Bühler FR.Kiowski W, et al.Cardiovasc Drugs Ther. 1990 Aug;4 Suppl 5:935-40. doi: 10.1007/BF02018296.Cardiovasc Drugs Ther. 1990.PMID:2076403Review.
Cited by
- Calcium channel blockers for primary Raynaud's phenomenon.Ennis H, Hughes M, Anderson ME, Wilkinson J, Herrick AL.Ennis H, et al.Cochrane Database Syst Rev. 2016 Feb 25;2(2):CD002069. doi: 10.1002/14651858.CD002069.pub5.Cochrane Database Syst Rev. 2016.PMID:26914257Free PMC article.Review.
- Calcium channel blockers for primary and secondary Raynaud's phenomenon.Rirash F, Tingey PC, Harding SE, Maxwell LJ, Tanjong Ghogomu E, Wells GA, Tugwell P, Pope J.Rirash F, et al.Cochrane Database Syst Rev. 2017 Dec 13;12(12):CD000467. doi: 10.1002/14651858.CD000467.pub2.Cochrane Database Syst Rev. 2017.PMID:29237099Free PMC article.Review.
Publication types
MeSH terms
Substances
Related information
LinkOut - more resources
Full Text Sources
Medical