Review
doi: 10.3390/life11030199.The Emerging Roles of Antioxidant Enzymes by Dietary Phytochemicals in Vascular Diseases
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- PMID:33806594
- PMCID: PMC8001043
- DOI: 10.3390/life11030199
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Review
The Emerging Roles of Antioxidant Enzymes by Dietary Phytochemicals in Vascular Diseases
Seung Eun Lee et al. Life (Basel)..
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Abstract
Vascular diseases are major causes of death worldwide, causing pathologies including diabetes, atherosclerosis, and chronic obstructive pulmonary disease (COPD). Exposure of the vascular system to a variety of stressors and inducers has been implicated in the development of various human diseases, including chronic inflammatory diseases. In the vascular wall, antioxidant enzymes form the first line of defense against oxidative stress. Recently, extensive research into the beneficial effects of phytochemicals has been conducted; phytochemicals are found in commonly used spices, fruits, and herbs, and are used to prevent various pathologic conditions, including vascular diseases. The present review aims to highlight the effects of dietary phytochemicals role on antioxidant enzymes in vascular diseases.
Keywords: antioxidant enzymes; bioactive compounds; vascular diseases.
Conflict of interest statement
The authors declare no conflict of interest.
Figures
Signaling pathways involved in antioxidant enzymes.
Antioxidant enzymes in vascular protection. Oxidative stress and inflammation in the vascular system response to multiple kinds of inducers, subsequently leading to several pathological conditions. This review supposed that induction of antioxidant enzyme expression provides cytoprotection against vascular injury and preserves vascular function.
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