Using carbon dioxide (CO₂) for stunning pigs at slaughter is common in Europe. The use of group stunning is a major advantage with CO₂, which is done without restraining the pigs and with minimized human contact. However, high concentrations of CO₂ have been known for decades to cause pain, fear and distress in pigs before loss of consciousness, and the stunning method is clearly associated with animal welfare concerns. This study reviewed the scientific literature to find recent developments or evaluations of alternative methods that could lead to the replacement of CO₂ for stunning pigs at slaughter. Potential alternative methods found in the literature were described and then assessed to identify specific research and development needs for their further development. Only 15 empirical studies were found in the search of peer-reviewed literature since 2004, which is less than one per year. Furthermore, half of the studies focused on evaluating methods to improve high-concentration CO₂ stunning rather than an alternative to CO₂. Since no clear alternative has emerged, nor a method to improve CO₂ stunning, there is obviously a strong need to focus research and development to find solutions for improving animal welfare when stunning pigs at slaughter.