Movatterモバイル変換

[0]ホーム
URL:

Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
Thehttps:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

NIH NLM Logo
Log inShow account info
Access keysNCBI HomepageMyNCBI HomepageMain ContentMain Navigation
pubmed logo
Advanced Clipboard
User Guide

Actions

Share

Review
.1987 Nov-Dec;9(6):1102-8.
doi: 10.1093/clinids/9.6.1102.

AIDS in the pre-AIDS era

Affiliations
Review

AIDS in the pre-AIDS era

D Huminer et al. Rev Infect Dis.1987 Nov-Dec.

Abstract

A search of the medical literature published since 1950 disclosed 19 cases of probable AIDS reported before the start of the current epidemic. These cases retrospectively met the Centers for Disease Control's surveillance definition of the syndrome and had a clinical course suggestive of AIDS. The reports originated from North America, Western Europe, Africa, and the Middle East. The mean age of patients was 37 years, and the ratio of male to female patients was 1.7:1. Sixteen patients had opportunistic infections(s) without Kaposi's sarcoma. The remainder had disseminated Kaposi's sarcoma. The commonest opportunistic infection was Pneumocystis carinii pneumonia. Two patients were reported to be homosexual. Three others had been living in Africa, and one patient was born in Haiti. In two instances concurrent or subsequent opportunistic infection occurred in family members. All patients died 1 month to 6 years after the initial manifestation of disease. In view of the historical data, unrecognized cases of AIDS appear to have occurred sporadically in the pre-AIDS era.

PIP: Since 1950, medical literature revealed the possibility of the existence of 19 AIDS cases before the start of the current epidemic. These 19 cases were studied at Centers for Disease Control, and the details of the cases are reviewed in an attempt to discover whether or not AIDS was present even prior to the epidemic. Medical literature from 1950-1986 reports 19 cases from North America, Western Europe, Africa, and the Middle East. The study of each case was guided by 2 criteria: a) the presence of underlying cellular immunodeficiency and other opportunistic infections and b) the absence of underlying immunodeficiency and an account of a reduced resistance brought about by the disease. All of the 19 cases met both the Center for Disease Control's (CDC) and the study's definition of AIDS. Even though the etiologic agent of AIDS, HIV, has been discovered, cases continue to be diagnosed according to clinical criteria such as the existence of life-threatening opportunistic infection. None of the cases were recognized as AIDS cases at the time of diagnosis. The results showed that 16 patients had opportunistic infection and the remaining 3 had Kaposi's sarcoma. All of the patients, regardless of the infection type, died between 1 month to 6 years after the 1st signs of disease. These cases support the theory that AIDS existed prior to the current epidemic and is perhaps an old disease.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

Publication types

MeSH terms

Related information

LinkOut - more resources

Cite
Send To

NCBI Literature Resources

MeSHPMCBookshelfDisclaimer

The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited.

[8]ページ先頭
©2009-2025 Movatter.jp