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Review
.2020 Sep:116:480-493.
doi: 10.1016/j.neubiorev.2020.07.013. Epub 2020 Jul 16.

The development and use of facial grimace scales for pain measurement in animals

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Review

The development and use of facial grimace scales for pain measurement in animals

Jeffrey S Mogil et al. Neurosci Biobehav Rev.2020 Sep.

Abstract

The measurement of pain in animals is surprisingly complex, and remains a critical issue in veterinary care and biomedical research. Based on the known utility of pain measurement via facial expression in verbal and especially non-verbal human populations, "grimace scales" were first developed a decade ago for use in rodents and now exist for 10 different mammalian species. This review details the background context, historical development, features (including duration), psychometric properties, modulatory factors, and impact of animal grimace scales for pain.

Keywords: Facial expression; Grimace; Pain; Preclinical; Veterinary.

Copyright © 2020 Elsevier Ltd. All rights reserved.

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