Phylogenetic analyses with systematic taxon sampling show that mitochondria branch within Alphaproteobacteria
- PMID:32661403
- DOI: 10.1038/s41559-020-1239-x
Phylogenetic analyses with systematic taxon sampling show that mitochondria branch within Alphaproteobacteria
Abstract
Though it is well accepted that mitochondria originated from an alphaproteobacteria-like ancestor, the phylogenetic relationship of the mitochondrial endosymbiont to extant Alphaproteobacteria is yet unresolved. The focus of much debate is whether the affinity between mitochondria and fast-evolving alphaproteobacterial lineages reflects true homology or artefacts. Approaches such as site exclusion have been claimed to mitigate compositional heterogeneity between taxa, but this comes at the cost of information loss, and the reliability of such methods is so far unproven. Here we demonstrate that site-exclusion methods produce erratic phylogenetic estimates of mitochondrial origin. Thus, previous phylogenetic hypotheses on the origin of mitochondria based on pretreated datasets should be re-evaluated. We applied alternative strategies to reduce phylogenetic noise by systematic taxon sampling while keeping site substitution information intact. Cross-validation based on a series of trees placed mitochondria robustly within Alphaproteobacteria, sharing an ancient common ancestor with Rickettsiales and currently unclassified marine lineages.
Comment in
- Reply to: Phylogenetic affiliation of mitochondria with Alpha-II and Rickettsiales is an artefact.Fan L, Wu D, Goremykin V, Trost K, Knopp M, Zhang C, Martin WF, Zhu R.Fan L, et al.Nat Ecol Evol. 2022 Dec;6(12):1832-1835. doi: 10.1038/s41559-022-01896-8. Epub 2022 Oct 24.Nat Ecol Evol. 2022.PMID:36280779No abstract available.
- Phylogenetic affiliation of mitochondria with Alpha-II and Rickettsiales is an artefact.Martijn J, Vosseberg J, Guy L, Offre P, Ettema TJG.Martijn J, et al.Nat Ecol Evol. 2022 Dec;6(12):1829-1831. doi: 10.1038/s41559-022-01871-3. Epub 2022 Oct 24.Nat Ecol Evol. 2022.PMID:36280780No abstract available.
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