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Lumbar Puncture

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Lumbar Puncture

Louis A. Jane et al.
Free Books & Documents

Excerpt

Lumbar puncture (LP), also referred to as “spinal tap,” is a commonly performed procedure that involves obtaining and sampling cerebrospinal fluid from the spinal cord. It was developed by Heinrich Quincke in the late 19th Century. It is the gold standard diagnostic procedure in the diagnosis of meningitis, subarachnoid hemorrhage, and certain neurological disorders. It is also used in the measurement of intracranial pressure and administration of medications or diagnostic agents.

Copyright © 2025, StatPearls Publishing LLC.

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Conflict of interest statement

Disclosure:Louis Jane declares no relevant financial relationships with ineligible companies.

Disclosure:Anton Wray declares no relevant financial relationships with ineligible companies.

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References

    1. Pearce JM. Walter Essex Wynter, Quincke, and lumbar puncture. J Neurol Neurosurg Psychiatry. 1994 Feb;57(2):179. - PMC - PubMed
    1. Doherty CM, Forbes RB. Diagnostic Lumbar Puncture. Ulster Med J. 2014 May;83(2):93-102. - PMC - PubMed
    1. Wright BL, Lai JT, Sinclair AJ. Cerebrospinal fluid and lumbar puncture: a practical review. J Neurol. 2012 Aug;259(8):1530-45. - PubMed
    1. Hogan QH. Epidural anatomy: new observations. Can J Anaesth. 1998 May;45(5 Pt 2):R40-8. - PubMed
    1. Engelborghs S, Niemantsverdriet E, Struyfs H, Blennow K, Brouns R, Comabella M, Dujmovic I, van der Flier W, Frölich L, Galimberti D, Gnanapavan S, Hemmer B, Hoff E, Hort J, Iacobaeus E, Ingelsson M, Jan de Jong F, Jonsson M, Khalil M, Kuhle J, Lleó A, de Mendonça A, Molinuevo JL, Nagels G, Paquet C, Parnetti L, Roks G, Rosa-Neto P, Scheltens P, Skårsgard C, Stomrud E, Tumani H, Visser PJ, Wallin A, Winblad B, Zetterberg H, Duits F, Teunissen CE. Consensus guidelines for lumbar puncture in patients with neurological diseases. Alzheimers Dement (Amst) 2017;8:111-126. - PMC - PubMed

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