Motion sickness is a common and complex syndrome that occurs in response to the real or perceived motion. Its presentation can be diverse, including the gastrointestinal, central nervous system, and autonomic symptoms. There is considerable individual variability in motion sickness susceptibility, as some individuals may suffer from minimal provocation and in others, it may be very difficult to elicit symptoms.

Motion sickness symptoms were first described by Hippocrates, who wrote, “sailing on the sea proves that motion disorders the body.” The main symptom of motion sickness, nausea, is derived fromnaus, the Greek word for ship (e.g., nautical).

Motion sickness occurs when there is a mismatch between actual versus expected sensory inputs. Although the exact neurobiological mechanism is unclear, many countermeasures have been developed to prevent and alleviate this condition.

Disclosure:Veronica Takov declares no relevant financial relationships with ineligible companies.

Disclosure:Prasanna Tadi declares no relevant financial relationships with ineligible companies.