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.2018 Sep 19;14(619):1660-1664.

[Negative symptoms in schizophrenia - overview and practical implications]

[Article in French]
Affiliations
  • PMID:30230774

[Negative symptoms in schizophrenia - overview and practical implications]

[Article in French]
Federica Klaus et al. Rev Med Suisse..

Abstract
in English, French

Negative symptoms in schizophrenia can be categorized in the symptom-dimensions of apathy (avolition, anhedonia and social withdrawal) and reduced expression (blunted affect and alogia). Based on the strong relevance for the quality of life and functional outcome during the course of an illness, a differentiated diagnostic and therapeutic approach is of high importance. Such a differentiation specifies primary negative symptoms (regarded as an integral part of schizophrenia) and secondary negative symptoms (regarded as a result of positive symptoms, comorbid depression, effects of antipsychotic medication, substance abuse or social deprivation). The following overview will summarize the various aspects of negative symptoms and discuss current diagnostic and therapeutic recommendations.

Les symptômes négatifs de la schizophrénie peuvent être classés en catégories de symptômes d’apathie (anhédonie, retrait social, avolition) et de diminution de l’expressivité (alogie et émoussement affectif). Les symptômes négatifs affectent gravement la qualité de vie et le pronostic fonctionnel. Il convient de souligner l’importance d’une différenciation diagnostique entre symptômes négatifs primaires (considérés comme partie intégrante de la physiopathologie schizophrénique) et symptômes négatifs secondaires (considérés comme conséquence de symptômes positifs, d’une dépression, des effets secondaires des antipsychotiques, d’abus de substances ou d’isolement social). Cet article résume les divers aspects des symptômes négatifs et discute les recommandations diagnostiques et thérapeutiques.

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Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article.

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