Movatterモバイル変換

[0]ホーム
URL:

Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
Thehttps:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

NIH NLM Logo
Log inShow account info
Access keysNCBI HomepageMyNCBI HomepageMain ContentMain Navigation
pubmed logo
Advanced Clipboard
User Guide

Full text links

Public Library of Science full text link Public Library of Science Free PMC article
Full text links

Actions

Share

.2018 Aug 23;13(8):e0202741.
doi: 10.1371/journal.pone.0202741. eCollection 2018.

Spleen size evaluation in children: Time to define splenomegaly for pediatric surgeons and pediatricians

Affiliations

Spleen size evaluation in children: Time to define splenomegaly for pediatric surgeons and pediatricians

Gloria Pelizzo et al. PLoS One..

Abstract

Background: We determined the range of normal spleen dimensions evaluated by ultrasonography (US) in children according to sex and age and the relationship between splenic measurements, auxological data and body proportions, in order to define splenomegaly parameters in support of the surgical mini-invasive approaches in pediatrics.

Methods: We prospectively examined 317 caucasian children of both sexes. The patients were divided into three groups: 0-3 years; 4-10 years; 11-18 years. Sex, weight, height/length, body mass index (BMI), waist circumference and xipho-pubic distance were determined for each child. US spleen evaluation included longitudinal/antero-posterior/transverse diameters, transverse area and volume. Spleen volume/abdominal volume, longitudinal spleen diameter/longitudinal left kidney diameter and longitudinal spleen diameter/xipho-pubic distance ratios were also calculated.

Results: For caucasian subjects, in different age groups spleen volume, transverse area and diameter increased while the spleen/abdominal volume ratio decreased significantly (p<0.001). A significant (p<0.001) decrease in longitudinal spleen diameter/xipho-pubic distance ratio was noted between the 0-3 years group and both 4-10 and 11-18 years group. Age and auxological data, except BMI, showed a high correlation with spleen dimension (r≥0.8).

Conclusions: The current concept of splenomegaly is not applicable in pediatric surgery. A dedicated classification of splenomegaly is needed for children and would improve the safety and feasibility of treatment.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Curves of the model based reference limits (3th-97th) for the spleen dimensions.
Spleen diameters are natural scale; all other measures are log-transformed for the purpose of this analysis.
Fig 2
Fig 2. Spleen size in adults [16, 17] and children.
Reference limits according to age and our results, are reported as normal values in children.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Hassan ME, Al Ali K. Massive splenomegaly in children: laparoscopic versus open splenectomy. JSLS. 2014;18(3). - PMC - PubMed
    1. Kim DJ, Chung JH. Long-term results of laparoscopic splenectomy in pediatric chronic immune thrombocytopenic purpura. Ann Surg Treat Res. 2014;86:314–8. 10.4174/astr.2014.86.6.314 - DOI - PMC - PubMed
    1. Al-Salem AH. Splenectomy for children with thalassemia: total or partial splenectomy, open or laparoscopic splenectomy. J Pediatr Hematol Oncol. 2014. February 26 [Epub ahead of print] 10.1097/MPH.0000000000000121 . - DOI - PubMed
    1. Vecchio R, Marchese S, Intagliata E. Pediatric laparoscopic splenectomy in a department of general surgery. Updates Surg. 2013;65:337–8. 10.1007/s13304-012-0186-8 - DOI - PubMed
    1. Deng XG, Maharjan A, Tang J, Qiu RL, Wu YH, Zhang J, et al. A modified laparoscopic splenectomy for massive splenomegaly in children with hematological disorder: a single institute retrospective clinical research. Pediatr Surg Int 2012;28:1201–9. 10.1007/s00383-012-3215-2 - DOI - PubMed

MeSH terms

Related information

Grants and funding

The authors received no specific funding for this work.

LinkOut - more resources

Full text links
Public Library of Science full text link Public Library of Science Free PMC article
Cite
Send To

NCBI Literature Resources

MeSHPMCBookshelfDisclaimer

The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited.

[8]ページ先頭
©2009-2025 Movatter.jp