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.2018 Aug;85(8-9):738-739.
doi: 10.1002/mrd.23047. Epub 2018 Aug 29.

ITGA1 is upregulated in response to oxygen over time in a BMP4 model of trophoblast

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ITGA1 is upregulated in response to oxygen over time in a BMP4 model of trophoblast

Rowan M Karvas et al. Mol Reprod Dev.2018 Aug.
No abstract available

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Conflict of interest statement

Conflict of Interest Statement: The authors have no conflicts of interest to declare

Figures

Figure 1.
Figure 1.
ITGA1 expression in BAP-differentiated hESCs exposed to a high oxygen environment (20%, atmospheric) and a lower, physiological oxygen environment (5%). (A) Immunofluorescence images of H1 (top) and H9 (bottom) hESCs treated for 6 days with BAP. ITGA1 (green) is expressed in syncytialized cells also stained positive for CGB (red). (B) Expression of ITGA1 over time, quantified as total fluorescence intensity per image, averaged across three images per experiment, and three experiments per time point. Both H1 and H9 cells significantly upregulate ITGA1 over time in response to high oxygen (2-way ANOVA interaction of time and oxygen=***p<0.0001, **p<0.003).
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References

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