Review
doi: 10.1111/1756-185X.13218. Epub 2017 Nov 19.The genetics of Kawasaki disease
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- PMID:29152908
- DOI: 10.1111/1756-185X.13218
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Review
The genetics of Kawasaki disease
Yoshihiro Onouchi. Int J Rheum Dis.2018 Jan.
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Abstract
Kawasaki disease (KD) is a complex disorder which affects genetically susceptible infants and children. Several susceptibility genes (e.g., ITPKC, CASP3, CD40 and ORAI) and chromosomal regions have been identified through genome-wide association and genome-wide linkage studies to have association with KD. Knowledge of susceptibility genes involved in the pathogenesis of KD may provide new insights into diagnosis and treatment of this condition. However, there is much that we still do not know about the genetic basis of KD.
Keywords: Kawasaki disease; genetic variants; susceptibility gene.
© 2017 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.
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