Aspirin and Nonsteroidal Antiinflammatory Drugs Hypersensitivity and Management
- PMID:28965637
- DOI: 10.1016/j.iac.2017.07.008
Aspirin and Nonsteroidal Antiinflammatory Drugs Hypersensitivity and Management
Abstract
Aspirin and nonsteroidal antiinflammatory drugs (NSAIDs) are widely used in the United States and throughout the world for a variety of indications. Several unique hypersensitivity syndromes exist to this class of medications, making them one of the common reasons for consultation to the allergist. The lack of any laboratory-based diagnostic studies to assist in identifying the culprits in these reactions make evaluation of aspirin and NSAID hypersensitivity challenging. Identifying patients appropriate for oral challenge and/or desensitization protocols is the standard pragmatic approach to this issue when it arises.
Keywords: Aspirin; Aspirin-exacerbated respiratory disease; Chronic spontaneous urticaria; Desensitization; Nonsteroidal antiinflammatory drugs; Oral challenge.
Copyright © 2017 Elsevier Inc. All rights reserved.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical