Movatterモバイル変換

[0]ホーム
URL:

Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
Thehttps:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

NIH NLM Logo
Log inShow account info
Access keysNCBI HomepageMyNCBI HomepageMain ContentMain Navigation
pubmed logo
Advanced Clipboard
User Guide

Full text links

Springer full text link Springer
Full text links

Actions

Review
.2017 Apr;19(4):26.
doi: 10.1007/s11906-017-0723-4.

Antihypertensive Effects of Probiotics

Affiliations
Review

Antihypertensive Effects of Probiotics

Iñaki Robles-Vera et al. Curr Hypertens Rep.2017 Apr.

Abstract

Purpose of review: The present review focuses in the hypertension-associated changes in the microbiota and the current insights regarding the impact of probiotics on blood pressure in animal models and in human hypertensive patients.

Recent findings: Gut dysbiosis in hypertension is characterized by (i) the gut microbioma that is less diverse and less rich with an increased Firmicutes/Bacteroidetes ratio and (ii) a decrease in acetate- and butyrate-producing bacteria and an increase in lactate-producing bacterial populations. The meta-analysis of the human studies supports that supplementation with probiotics reduces blood pressure. The mechanism of this antihypertensive effect of probiotics and its protective effect on endothelial function has not been fully elucidated. Further investigations are needed to clarify if the effects of probiotic bacteria result from the changes in the gut microbiota and its metabolic by-products; the restoration of the gut barrier function; and the effects on endotoxemia, inflammation, and renal sympathetic nerve activity.

Keywords: Endothelial dysfunction; Gut microbiota; Hypertension; Probiotic bacteria.

PubMed Disclaimer

References

    1. Nature. 2009 Oct 29;461(7268):1282-6 - PubMed
    1. Blood Press. 2014 Feb;23(1):3-16 - PubMed
    1. Hypertension. 2015 Jun;65(6):1331-40 - PubMed
    1. J Clin Diagn Res. 2015 Mar;9(3):KC01-4 - PubMed
    1. Clin Sci (Lond). 2014 Jul;127(1):33-45 - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources

Full text links
Springer full text link Springer
Cite
Send To

NCBI Literature Resources

MeSHPMCBookshelfDisclaimer

The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited.

[8]ページ先頭
©2009-2025 Movatter.jp