.2015 Oct;27(5):563-77.

doi: 10.5021/ad.2015.27.5.563. Epub 2015 Oct 2.

Consensus Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): General Management and Topical Treatment

Jung Eun Kim¹, Hyun Jeong Kim², Bark-Lynn Lew³, Kyung Ho Lee¹, Seung Phil Hong⁴, Yong Hyun Jang⁵, Kui Young Park⁶, Seong Jun Seo⁶, Jung Min Bae¹, Eung Ho Choi⁷, Ki Beom Suhr⁸, Seung Chul Lee⁹, Hyun Chang Ko¹⁰, Young Lip Park¹¹, Sang Wook Son¹², Young Jun Seo¹³, Yang Won Lee¹⁴, Sang Hyun Cho¹, Chun Wook Park¹⁵, Joo Young Roh¹⁶

Affiliations

¹ Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
² Department of Dermatology, Seoul Medical Center, Kyung Hee University College of Medicine, Seoul, Korea.
³ Department of Dermatology, Kyung Hee University College of Medicine, Seoul, Korea.
⁴ Department of Dermatology, Dankook University Medical College, Cheonan, Korea.
⁵ Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea.
⁶ Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
⁷ Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea.
⁸ Department of Dermatology, SA Dermatology Clinic, Daejeon, Korea.
⁹ Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
¹⁰ Department of Dermatology, Pusan National University School of Medicine, Busan, Korea.
¹¹ Department of Dermatology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
¹² Department of Dermatology, Korea University College of Medicine, Seoul, Korea.
¹³ Department of Dermatology, Chungnam National University College of Medicine, Daejeon, Korea.
¹⁴ Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
¹⁵ Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
¹⁶ Department of Dermatology, Gachon University Gil Medical Center, Incheon, Korea.

PMID:26512171
PMCID: PMC4622891
DOI: 10.5021/ad.2015.27.5.563

Consensus Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): General Management and Topical Treatment

Jung Eun Kim et al. Ann Dermatol.2015 Oct.

.2015 Oct;27(5):563-77.

doi: 10.5021/ad.2015.27.5.563. Epub 2015 Oct 2.

Authors

Affiliations

¹ Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
² Department of Dermatology, Seoul Medical Center, Kyung Hee University College of Medicine, Seoul, Korea.
³ Department of Dermatology, Kyung Hee University College of Medicine, Seoul, Korea.
⁴ Department of Dermatology, Dankook University Medical College, Cheonan, Korea.
⁵ Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea.
⁶ Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
⁷ Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea.
⁸ Department of Dermatology, SA Dermatology Clinic, Daejeon, Korea.
⁹ Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
¹⁰ Department of Dermatology, Pusan National University School of Medicine, Busan, Korea.
¹¹ Department of Dermatology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
¹² Department of Dermatology, Korea University College of Medicine, Seoul, Korea.
¹³ Department of Dermatology, Chungnam National University College of Medicine, Daejeon, Korea.
¹⁴ Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
¹⁵ Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
¹⁶ Department of Dermatology, Gachon University Gil Medical Center, Incheon, Korea.

PMID:26512171
PMCID: PMC4622891
DOI: 10.5021/ad.2015.27.5.563

Abstract

Background: Since the treatment guidelines for atopic dermatitis (AD) were released by the Korean Atopic Dermatitis Association (KADA) work group in 2006, there have been several advances in AD management.

Objective: We aimed to establish updated evidence- and experience-based treatment guidelines for Korean AD.

Methods: We collected a database of references from relevant systematic AD reviews and guidelines regarding general AD management such as bathing and skin care, avoidance of exacerbating factors, education and psychosocial support, and the use of moisturizers and topical anti-inflammatory and antipruritic drugs. Evidence for each statement was graded and the strength of the recommendation for each statement classified. Thirty-nine KADA council members participated in three rounds of voting to establish an expert consensus of recommendations.

Results: Basic AD treatment includes proper bathing and skin care, avoidance of exacerbating factors, proper education and psychosocial support, and use of moisturizers. The regular use of moisturizer has a steroid-sparing effect and reduces relapse episodes. The short- and long-term use of topical corticosteroids and calcineurin inhibitors improves AD symptoms and should be encouraged to use in an active and proactive treatment. Wet-wrap therapy can be used for rapid recovery of acute exacerbation. Topical antipruritic drugs cannot be recommended for the treatment of AD.

Conclusion: This report provides up-to-date evidence- and experience-based treatment guidelines for AD regarding general management and topical treatment. In addition, the average agreement scores obtained by a panel of experts based on the Korean healthcare system and patient adherence are presented.

Keywords: Administration; Guideline; Therapeutics; topical.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: Young Roh is a clinical trials investigator for Astellas and Novartis. Hyun Chang Ko is a clinical trials investigator for Astellas.

Figures

Fig. 1. The fingertip unit (FTU) method is used in to determine the amount of topical corticosteroids (TCS) or calcineurin inhibitors to apply. The amount from the distal skin crease to the tip of an adult patient's index finger is equivalent to approximately 0.5 g TCS. 1 FTU generally covers the surface area of two palms.

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Consensus Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): General Management and Topical Treatment

Affiliations

Consensus Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): General Management and Topical Treatment

Authors

Affiliations

Abstract

Conflict of interest statement

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