doi: 10.1128/JCM.00336-15. Epub 2015 May 6.
Molecular Diagnosis of Abdominal Armillifer grandis Pentastomiasis in the Democratic Republic of Congo
Affiliations
- PMID:25948609
- PMCID: PMC4473205
- DOI: 10.1128/JCM.00336-15
Item in Clipboard
Molecular Diagnosis of Abdominal Armillifer grandis Pentastomiasis in the Democratic Republic of Congo
Dennis Tappe et al. J Clin Microbiol.2015 Jul.
Display options
Format
Display options
Format
Abstract
Pentastomiasis is an emerging snake-borne parasitic zoonosis in the tropics. We describe a molecular and morphological study to diagnose a cluster of asymptomatic abdominal human infections caused by Armillifer grandis. The findings may indicate a silent epidemic in a rural area where severe symptomatic ocular cases with the same parasite species have recently surfaced. Molecular diagnostics are of increasing importance when patient material from remote areas cannot be thoroughly examined locally for logistic reasons.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.
Figures
Map of the Democratic Republic of Congo showing locations of Kole and Katako Kombe, Sankuru district, part of the Kasai-Oriental province (outlined in red).
Microscopy of larval pentastomid parasites recovered during abdominal surgery in the Democratic Republic of Congo. Histological section through completely necrotic formalin-fixed, paraffin-embedded pentastomid larva from one patient. Only the highly decay-refractory folded cuticular remnants (red folded membranes in the background) and the abundant round sclerotized openings of the cuticle remain identifiable. The arrows point exemplarily to four of the openings: two openings in transverse section (horizontal arrows) and two openings in oblique section (oblique arrows). The second specimen from the same patient showed similar structures. Periodic acid-Schiff stain, magnification ×200. For comparison of the cuticular openings depicted here, see Fig. 4 in reference 1 and Fig. 2 in reference 5.
Similar articles
- Co-infections in Visceral Pentastomiasis, Democratic Republic of the Congo.Tappe D, Sulyok M, Riu T, Rózsa L, Bodó I, Schoen C, Muntau B, Babocsay G, Hardi R.Tappe D, et al.Emerg Infect Dis. 2016 Aug;22(8):1333-9. doi: 10.3201/eid2208.151895.Emerg Infect Dis. 2016.PMID:27434739Free PMC article.
- Imported Armillifer pentastomiasis: report of a symptomatic infection in The Netherlands and mini-review.Tappe D, Dijkmans AC, Brienen EA, Dijkmans BA, Ruhe IM, Netten MC, van Lieshout L.Tappe D, et al.Travel Med Infect Dis. 2014 Mar-Apr;12(2):129-33. doi: 10.1016/j.tmaid.2013.10.011. Epub 2013 Oct 31.Travel Med Infect Dis. 2014.PMID:24211241Review.
- Ocular pentastomiasis in the Democratic Republic of the Congo.Sulyok M, Rózsa L, Bodó I, Tappe D, Hardi R.Sulyok M, et al.PLoS Negl Trop Dis. 2014 Jul 24;8(7):e3041. doi: 10.1371/journal.pntd.0003041. eCollection 2014 Jul.PLoS Negl Trop Dis. 2014.PMID:25058608Free PMC article.
- Diagnosis of human visceral pentastomiasis.Tappe D, Büttner DW.Tappe D, et al.PLoS Negl Trop Dis. 2009;3(2):e320. doi: 10.1371/journal.pntd.0000320. Epub 2009 Feb 24.PLoS Negl Trop Dis. 2009.PMID:19238218Free PMC article.
- [Progress of research on clinical manifestations and diagnosis of human pentastomiasis].Zhang LL, Chen JX.Zhang LL, et al.Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2012 Apr;24(2):222-7.Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2012.PMID:22799176Review.Chinese.
Cited by
- Armillifer-Infected Snakes Sold at Congolese Bushmeat Markets Represent an Emerging Zoonotic Threat.Hardi R, Babocsay G, Tappe D, Sulyok M, Bodó I, Rózsa L.Hardi R, et al.Ecohealth. 2017 Dec;14(4):743-749. doi: 10.1007/s10393-017-1274-5. Epub 2017 Oct 13.Ecohealth. 2017.PMID:29030787Free PMC article.
- Co-infections in Visceral Pentastomiasis, Democratic Republic of the Congo.Tappe D, Sulyok M, Riu T, Rózsa L, Bodó I, Schoen C, Muntau B, Babocsay G, Hardi R.Tappe D, et al.Emerg Infect Dis. 2016 Aug;22(8):1333-9. doi: 10.3201/eid2208.151895.Emerg Infect Dis. 2016.PMID:27434739Free PMC article.
- Armillifer Infections in Humans: A Systematic Review.Ioannou P, Vamvoukaki R.Ioannou P, et al.Trop Med Infect Dis. 2019 May 16;4(2):80. doi: 10.3390/tropicalmed4020080.Trop Med Infect Dis. 2019.PMID:31100831Free PMC article.Review.
- A Case of Pentastomiasis at the Left Maxilla Bone in a Patient with Thyroid Cancer.Cho ES, Jung SW, Jung HD, Lee IY, Yong TS, Jeong SJ, Kim HS.Cho ES, et al.Korean J Parasitol. 2017 Aug;55(4):433-437. doi: 10.3347/kjp.2017.55.4.433. Epub 2017 Aug 31.Korean J Parasitol. 2017.PMID:28877577Free PMC article.
References
MeSH terms
LinkOut - more resources
Full Text Sources
Medical