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Review
.2015;15(1):57-69.
doi: 10.2174/1871529x15666150108114810.

Sepsis pathophysiology and anesthetic consideration

Affiliations
Review

Sepsis pathophysiology and anesthetic consideration

Koichi Yuki et al. Cardiovasc Hematol Disord Drug Targets.2015.

Abstract

Sepsis remains to be a significant health care issue associated with high mortality and healthcare cost, despite the extensive effort to better understand the pathophysiology of the sepsis. Recently updated clinical guideline for severe sepsis and septic shock, "Surviving Sepsis Campaign 2012", emphasizes the importance of early goal-directed therapy, which can be implemented in intraoperative management of sepsis patients. Herein, we review the updates of current guideline and discuss its application to anesthesic management. Furthermore, we review the recent advance in knowledge of sepsis pathophysiology, focusing on immune modulation, which may lead to new clinical therapeutic approach to sepsis.

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Conflict of interest statement

Conflict of Interest: The author(s) confirm that this article content has no conflict of interest.

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References

    1. Geroulanos S, Douka ET. Historical perspective of the word “sepsis”. Intensive Care Med. 2006;32:2077. - PubMed
    1. Budelmann G. Hugo Schottmuller, 1867-1936. The problem of sepsis. Internist (Berl) 1969;10:92–101. - PubMed
    1. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. Am. Coll. Chest Physicians/Society of Critical Care Medicine Chest. 1992;101:1644–55. - PubMed
    1. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013;41:580–637. - PubMed
    1. Eissa D, Carton EG, Buggy DJ. Anaesthetic management of patients with severe sepsis. Br J Anaesth. 2010;105:734–43. - PubMed

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