The provision of civil liberties to LGBT persons has become part of a global movement in societies across the world. In Brazil, a recent judicial ruling for the first time established the right for homosexual couples to enter into civil unions, despite the presence of widespread disapproval of homosexuality among the population and opposition from prominent religious groups. Picking up on this issue, the following study examines whether religion may factor into the attitudes Brazilians hold toward homosexuality and same-sex civil unions. Using data from the Brazilian Social Research Survey, we find that the most restrictive views toward homosexuality and the strongest opposition to same-sex civil unions are most prevalent among devoted followers of historical Protestant, Pentecostal, and Catholic faith traditions, whereas adherents of Afro-Brazilian and spiritist religions, as well as those with no religious commitment, are inclined to assume a more tolerant moral posture toward such issues. The findings point to religion as a potential influence in future public policy initiatives and social movements involving LGBT issues in Brazil.