A comprehensive review of sensitization and allergy to soy-based products
- PMID:24425446
- DOI: 10.1007/s12016-013-8404-9
A comprehensive review of sensitization and allergy to soy-based products
Abstract
Since 1943, cases of sensitization or allergy to soy-based formulas (SBFs) have been described without any consensus on their real prevalence. We identified the adjusted prevalence of IgE-mediated soy allergies in children and performed a secondary analysis of the impact of age (less than and more than 6 months). We performed a systematic review with meta-analysis of studies published from 1909 to 2013 in PubMed, Embase, LILACS, ARTEMISA, Cochrane, Bandolier, DARE and the GRADE system for grading quality. Results are presented in tables and graphs using a forest plot. The 40 studies identified established weighted prevalence of soy allergies of 0 to 0.5 % (0.27) for the general population, 0.4 to 3.1 % (1.9) for the referred population, and 0 to 12.9 % (2.7) for allergic children. Prevalence of sensitization after the use of SBFs is 8.7 and 8.8 %, depending on the method used. The prevalence of allergies to soy and IgE sensitization to the use of SBFs is less than reported. Not enough evidence exists to show a higher risk of allergy in infants younger than 6 months. The concern about soy allergy is no reason to postpone the use of SBFs in IgE-mediated cow's milk allergy infants until the age of 6 months.
Similar articles
- Prevalence of soy protein hypersensitivity in cow's milk protein-sensitive children in Korea.Ahn KM, Han YS, Nam SY, Park HY, Shin MY, Lee SI.Ahn KM, et al.J Korean Med Sci. 2003 Aug;18(4):473-7. doi: 10.3346/jkms.2003.18.4.473.J Korean Med Sci. 2003.PMID:12923320Free PMC article.
- Feeding a soy formula to children with cow's milk allergy: the development of immunoglobulin E-mediated allergy to soy and peanuts.Klemola T, Kalimo K, Poussa T, Juntunen-Backman K, Korpela R, Valovirta E, Vanto T.Klemola T, et al.Pediatr Allergy Immunol. 2005 Dec;16(8):641-6. doi: 10.1111/j.1399-3038.2005.00326.x.Pediatr Allergy Immunol. 2005.PMID:16343085Clinical Trial.
- Natural history of soy allergy and/or intolerance in children, and clinical use of soy-protein formulas.Cantani A, Lucenti P.Cantani A, et al.Pediatr Allergy Immunol. 1997 May;8(2):59-74. doi: 10.1111/j.1399-3038.1997.tb00146.x.Pediatr Allergy Immunol. 1997.PMID:9617775Review.
- Soy formula for prevention of allergy and food intolerance in infants.Osborn DA, Sinn J.Osborn DA, et al.Cochrane Database Syst Rev. 2004;(3):CD003741. doi: 10.1002/14651858.CD003741.pub2.Cochrane Database Syst Rev. 2004.Update in:Cochrane Database Syst Rev. 2006 Oct 18;(4):CD003741. doi: 10.1002/14651858.CD003741.pub4.PMID:15266499Updated.Review.
- Prevention of allergic disease in childhood: clinical and epidemiological aspects of primary and secondary allergy prevention.Halken S.Halken S.Pediatr Allergy Immunol. 2004 Jun;15 Suppl 16:4-5, 9-32. doi: 10.1111/j.1399-3038.2004.0148b.x.Pediatr Allergy Immunol. 2004.PMID:15125698Review.
Cited by
- New Frontiers: Precise Editing of Allergen Genes Using CRISPR.Brackett NF, Pomés A, Chapman MD.Brackett NF, et al.Front Allergy. 2022 Jan 17;2:821107. doi: 10.3389/falgy.2021.821107. eCollection 2021.Front Allergy. 2022.PMID:35386981Free PMC article.Review.
- The Impacts of Cholesterol, Oxysterols, and Cholesterol Lowering Dietary Compounds on the Immune System.Yanagisawa R, He C, Asai A, Hellwig M, Henle T, Toda M.Yanagisawa R, et al.Int J Mol Sci. 2022 Oct 13;23(20):12236. doi: 10.3390/ijms232012236.Int J Mol Sci. 2022.PMID:36293093Free PMC article.Review.
- Prevention and Management of Cow's Milk Allergy in Non-Exclusively Breastfed Infants.Vandenplas Y.Vandenplas Y.Nutrients. 2017 Jul 10;9(7):731. doi: 10.3390/nu9070731.Nutrients. 2017.PMID:28698533Free PMC article.Review.
- Retrospective Cohort Study Demonstrates Tolerance and Adherence to Pea-Based Complete Enteral Formula When Transitioned from a Previous Hypoallergenic Product.Withrow NA, Al-Tawil Y, Patterson PJ, Wilson M, Ryan E, Millovich V, Valentine CJ.Withrow NA, et al.Nutrients. 2024 Oct 3;16(19):3365. doi: 10.3390/nu16193365.Nutrients. 2024.PMID:39408332Free PMC article.
- Effects ofLactobacillus on the Differentiation of Intestinal Mucosa Immune Cells and the Composition of Gut Microbiota in Soybean-Sensitized Mice.Yang C, Zhu J, Bai J, Zhang J, Wu Z, Li X, Tong P, Chen H, Yang A.Yang C, et al.Foods. 2023 Feb 1;12(3):627. doi: 10.3390/foods12030627.Foods. 2023.PMID:36766155Free PMC article.
References
Publication types
MeSH terms
Substances
Related information
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical