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.2013 Jun 25:7:296.
doi: 10.3389/fnhum.2013.00296. eCollection 2013.

Misophonia: physiological investigations and case descriptions

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Misophonia: physiological investigations and case descriptions

Miren Edelstein et al. Front Hum Neurosci..

Abstract

Misophonia is a relatively unexplored chronic condition in which a person experiences autonomic arousal (analogous to an involuntary "fight-or-flight" response) to certain innocuous or repetitive sounds such as chewing, pen clicking, and lip smacking. Misophonics report anxiety, panic, and rage when exposed to trigger sounds, compromising their ability to complete everyday tasks and engage in healthy and normal social interactions. Across two experiments, we measured behavioral and physiological characteristics of the condition. Interviews (Experiment 1) with misophonics showed that the most problematic sounds are generally related to other people's behavior (pen clicking, chewing sounds). Misophonics are however not bothered when they produce these "trigger" sounds themselves, and some report mimicry as a coping strategy. Next, (Experiment 2) we tested the hypothesis that misophonics' subjective experiences evoke an anomalous physiological response to certain auditory stimuli. Misophonic individuals showed heightened ratings and skin conductance responses (SCRs) to auditory, but not visual stimuli, relative to a group of typically developed controls, supporting this general viewpoint and indicating that misophonia is a disorder that produces distinct autonomic effects not seen in typically developed individuals.

Keywords: auditory processing; autonomic response; aversive sounds; case reports; misophonia; skin conductance response; sound sensitivity.

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Figures

Figure 1
Figure 1
Average misophonic and control participants' skin conductance response to auditory and visual stimuli as a function of time.
Figure 2
Figure 2
Group means of controls and misophonics, per presentation condition (auditory and visual) for (A) subjective reports and (B) SCR.
Figure 3
Figure 3
Percentage of trials per index on the 5-point aversiveness scale, for controls and misophonics, during (A) auditory and (B) visual conditions.
Figure 4
Figure 4
Correlation of average aversiveness ratings and average SCR (in micro Siemens) for all trials across all subjects.
Figure 5
Figure 5
Correlation of average aversiveness ratings of stimuli (x- and y-axis) across conditions in misophonics and controls. Select stimuli identified by proximal text.
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