Review
doi: 10.1016/j.iac.2012.12.002. Epub 2013 Feb 1.NSAID single-drug-induced reactions
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- PMID:23639711
- DOI: 10.1016/j.iac.2012.12.002
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Review
NSAID single-drug-induced reactions
Katharine M Woessner et al. Immunol Allergy Clin North Am.2013 May.
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Abstract
Nonsteroidal anti-inflammatory drugs (NSAIDs) are cyclooxygenase inhibitors with analgesic, anti-inflammatory, antipyretic, and antithrombotic effects. NSAIDs have been implicated in a variety of drug-induced reactions that are proved as or suspected of being mediated through a host immune response. Single-drug-induced reactions are the hallmark of these types of reactions. The types of single-drug-induced reactions are the confluence of 2 variables, the structure of the drug and the specific types of immune responses. This article identifies reactions patterns and the NSAIDs most likely to elicit each immune response.
Copyright © 2013 Elsevier Inc. All rights reserved.
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