Review
doi: 10.3851/IMP2470. Epub 2012 Dec 7.Rapid diagnostic HCV antibody assays
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- PMID:23322678
- PMCID: PMC5791540
- DOI: 10.3851/IMP2470
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Review
Rapid diagnostic HCV antibody assays
Bryce D Smith et al. Antivir Ther.2012.
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Abstract
Approximately 4.1 million Americans have been infected with HCV and 45-85% of chronically infected persons are unaware of their status. Rapid anti-HCV assays can assist and expedite the identification of those unaware of their infection. Performance characteristics of pre-market rapid anti-HCV assays (Chembio, MedMira and OraSure) have been evaluated. Their sensitivity (78.9-99.3%) and specificity (80-100%) varied. Future investigations could include evaluation of rapid anti-HCV tests in persons who are coinfected with HCV and HIV, and development of rapid HCV-antigen tests and nucleic acid tests.
Conflict of interest statement
The authors declare no competing interests. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.
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