Attenuated psychosis and the schizophrenia prodrome: current status of risk identification and psychosis prevention
- PMID:23125875
- PMCID: PMC3483069
- DOI: 10.2217/npy.12.36
Attenuated psychosis and the schizophrenia prodrome: current status of risk identification and psychosis prevention
Abstract
Recent efforts in the prevention of schizophrenia have focused on defining psychosis-risk syndromes and evaluating treatments that can prevent transition to psychosis in these ultra-high risk groups. In this review, different kinds of prevention approaches are enumerated and necessary conditions for a disease-prevention strategy are summarized. The broad overlap as well as the significant difference between a schizophrenia prodrome and a 'psychosis-risk syndrome' is discussed and the present status of approaches to identify individuals at increased risk for developing psychosis and schizophrenia are critically examined along with evaluations on therapeutic interventions to reduce these risks. Finally, to conclude, recommendations for current best clinical practice and key questions for the future are suggested.
Conflict of interest statement
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.
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Website
American Psychiatric Association. DSM-5 Progress. 2012
www.dsm5.org . ▪▪ The current status of the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition proposals are provided on this site and regular updates are provided. Currently, ‘Attenuated Psychosis Syndrome’ is slated to be included in section three or the appendix of the manual, as a condition needing further study.
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