doi: 10.1007/s12288-008-0001-3. Epub 2008 Mar 19.
Sickle cell disease and malaria
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- PMID:23100918
- PMCID: PMC3453113
- DOI: 10.1007/s12288-008-0001-3
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Sickle cell disease and malaria
S H Arif. Indian J Hematol Blood Transfus.2007 Dec.
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Abstract
Malaria is most common infectious disease spread by female Anopheles mosquitoes especially in tropical and subtropical areas of the world. It is reported by WHO as a 4th leading cause of death in children across the developing countries. Unfortunately no vaccine is currently available. Sickle cell trait (HbAS) patients provide some resistance for malaria over normal persons (HbAA) or their homozygous state (HbSS) due to various reasons.
Keywords: Falciparum malaria; Sickle cell disease; Sickle cell trait.
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