The Oslo definitions for coeliac disease and related terms
- PMID:22345659
- PMCID: PMC3440559
- DOI: 10.1136/gutjnl-2011-301346
The Oslo definitions for coeliac disease and related terms
Abstract
Objective: The literature suggests a lack of consensus on the use of terms related to coeliac disease (CD) and gluten.
Design: A multidisciplinary task force of 16 physicians from seven countries used the electronic database PubMed to review the literature for CD-related terms up to January 2011. Teams of physicians then suggested a definition for each term, followed by feedback of these definitions through a web survey on definitions, discussions during a meeting in Oslo and phone conferences. In addition to 'CD', the following descriptors of CD were evaluated (in alphabetical order): asymptomatic, atypical, classical, latent, non-classical, overt, paediatric classical, potential, refractory, silent, subclinical, symptomatic, typical, CD serology, CD autoimmunity, genetically at risk of CD, dermatitis herpetiformis, gluten, gluten ataxia, gluten intolerance, gluten sensitivity and gliadin-specific antibodies.
Results: CD was defined as 'a chronic small intestinal immune-mediated enteropathy precipitated by exposure to dietary gluten in genetically predisposed individuals'. Classical CD was defined as 'CD presenting with signs and symptoms of malabsorption. Diarrhoea, steatorrhoea, weight loss or growth failure is required.' 'Gluten-related disorders' is the suggested umbrella term for all diseases triggered by gluten and the term gluten intolerance should not to be used. Other definitions are presented in the paper.
Conclusion: This paper presents the Oslo definitions for CD-related terms.
Conflict of interest statement
All authors declare that they have no conflicts of interest and therefore nothing to declare.
Comment in
- Some clarification is necessary on the Oslo definitions for coeliac disease-related terms.Di Sabatino A, Corazza GR.Di Sabatino A, et al.Gut. 2013 Jan;62(1):182. doi: 10.1136/gutjnl-2012-302613. Epub 2012 Jun 26.Gut. 2013.PMID:22735570No abstract available.
- Defining 'coeliac': Oslo Accord--or not?Marsh MN.Marsh MN.Gut. 2013 Nov;62(11):1669-70. doi: 10.1136/gutjnl-2013-304632. Epub 2013 Mar 20.Gut. 2013.PMID:23514748No abstract available.
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References
- Meeuwisse GW. Round table discussion. Diagnostic criteria in coeliac disease. Acta Paediatr. 1970;59:461–63.
- Janatuinen EK, Pikkarainen PH, Kemppainen TA, et al. A comparison of diets with and without oats in adults with celiac disease [see comments] N Engl J Med. 1995;333:1033–7. - PubMed
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