Movatterモバイル変換

[0]ホーム
URL:

Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
Thehttps:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

NIH NLM Logo
Log inShow account info
Access keysNCBI HomepageMyNCBI HomepageMain ContentMain Navigation
pubmed logo
Advanced Clipboard
User Guide

Full text links

Frontiers Media SA full text link Frontiers Media SA Free PMC article
Full text links

Actions

Share

.2012 Jan 3:2:269.
doi: 10.3389/fmicb.2011.00269. eCollection 2011.

Native morphology of influenza virions

Affiliations

Native morphology of influenza virions

Takeshi Noda. Front Microbiol..

Abstract

Influenza A virus is an enveloped virus with a segmented, single-strand, negative-sense RNA genome. Its virions show spherical or filamentous shapes of about 100 nm in diameter and occasionally irregular morphology, which exemplifies the pleomorphic nature of these virions. Each viral RNA segment forms a ribonucleoprotein complex (RNP), along with an RNA-dependent RNA polymerase complex and multiple copies of nucleoproteins; the RNPs reside in the enveloped virions. Here, we focus on electron microscopic analyses of influenza virions and RNPs. Based on the morphological and structural observations obtained by using electron microscopic techniques, we present a model of the native morphology of the influenza virion.

Keywords: electron microscopy; influenza virus; morphology.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Electron micrograph of influenza virions. The virions were purified by ultracentrifugation, and visualized by negative-staining EM. Bars, 200 nm.(A) Spherical virions [A/WSN/33 (H1N1)],(B) filamentous virions [A/Udorn/307/72 (H3N2)], and(C) irregular-shaped virions [A/Puerto Rico/8/34 (H1N1)].
Figure 2
Figure 2
Schematic diagram of influenza virions. Left, an elliptical virion; right, a filamentous virion. Note that both virions contain an organized set of eight RNPs at the end of the virion.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Akarsu H., Burmeister W. P., Petosa C., Petit I., Müller C. W., Ruigrok R. W., Baudin F. (2003). Crystal structure of the M1 protein-binding domain of the influenza A virus nuclear export protein (NEP/NS2). EMBO J. 22, 4646–465510.1093/emboj/cdg449 - DOI - PMC - PubMed
    1. Almeida J. D., Brand C. M. A. (1975). Morphological study of the internal component of influenza virus. J. Gen. Virol. 27, 313–31810.1099/0022-1317-27-3-313 - DOI - PubMed
    1. Almeida J. D., Waterson A. P. (1967). Some observations on the envelope of an influenza virus. J. Gen. Microbiol. 46, 107–110 - PubMed
    1. Amorim M. J., Bruce E. A., Reed E. K., Foeglein A., Mahen R., Stuart A. D., Digard P. (2011). A Rab11- and microtubule-dependent mechanism for cytoplasmic transport of influenza A virus viral RNA. J. Virol. 85, 4134–415610.1128/JVI.02606-10 - DOI - PMC - PubMed
    1. Apostolov K., Flewett T. H. (1965). Internal structure of influenza virus. Virology 26, 506–50810.1016/0042-6822(65)90014-0 - DOI - PubMed

Related information

LinkOut - more resources

Full text links
Frontiers Media SA full text link Frontiers Media SA Free PMC article
Cite
Send To

NCBI Literature Resources

MeSHPMCBookshelfDisclaimer

The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited.

[8]ページ先頭
©2009-2025 Movatter.jp