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Comment
.2011 Oct;49(1-2):1-3.
doi: 10.1016/j.molimm.2011.09.014. Epub 2011 Oct 13.

PD-L2 is predominantly expressed by Th2 cells

Comment

PD-L2 is predominantly expressed by Th2 cells

W Joost Lesterhuis et al. Mol Immunol.2011 Oct.

Abstract

In response to a recently published article by Messal et al. (2011) in which the authors show that PD-L2 is expressed by activated T cells and ligation results in suppression of T cell proliferation and cytokine secretion, we here report that PD-L2 is differentially expressed by the diverse Th subsets, with predominant expression by Th2 cells.

Copyright © 2011 Elsevier Ltd. All rights reserved.

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