Review
doi: 10.1051/medsci/2011275019. Epub 2011 May 25.[Potential of cell penetrating peptides for cell drug delivery]
[Article in French]
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- PMID:21609675
- DOI: 10.1051/medsci/2011275019
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Review
[Potential of cell penetrating peptides for cell drug delivery]
[Article in French]
Cathy Poillot et al. Med Sci (Paris).2011 May.
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Abstract
The interest of the scientific community for cell penetrating peptides (CPP) has been growing exponentially for these last years, and the list of novel CPP is increasing. These peptides are powerful tools for the delivery of cargoes to their site of action. Indeed, several drugs that cannot translocate through the cell plasma membrane have been successfully delivered into cells when grafted to a CPP. Various cargoes have been linked to CPP, such as oligonucleotides, pharmacologically active drugs, contrast agents for imaging, or nanoparticles as platforms for multigrafting purposes… This review illustrates the fabulous potential of CPP and the diversity of their use, but their most interesting application appears their future clinical use for the treatment of various pathological conditions.
© 2011 médecine/sciences - Inserm / SRMS.
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