Minimising oil droplet size using ultrasonic emulsification
- PMID:19321375
- DOI: 10.1016/j.ultsonch.2009.02.008
Minimising oil droplet size using ultrasonic emulsification
Abstract
The efficient production of nanoemulsions, with oil droplet sizes of less than 100nm would facilitate the inclusion of oil soluble bio-active agents into a range of water based foods. Small droplet sizes lead to transparent emulsions so that product appearance is not altered by the addition of an oil phase. In this paper, we demonstrate that it is possible to create remarkably small transparent O/W nanoemulsions with average diameters as low as 40nm from sunflower oil. This is achieved using ultrasound or high shear homogenization and a surfactant/co-surfactant/oil system that is well optimised. The minimum droplet size of 40nm, was only obtained when both droplet deformability (surfactant design) and the applied shear (equipment geometry) were optimal. The time required to achieve the minimum droplet size was also clearly affected by the equipment configuration. Results at atmospheric pressure fitted an expected exponential relationship with the total energy density. However, we found that this relationship changes when an overpressure of up to 400kPa is applied to the sonication vessel, leading to more efficient emulsion production. Oil stability is unaffected by the sonication process.
Similar articles
- Nanoemulsions prepared by a low-energy emulsification method applied to edible films.Bilbao-Sáinz C, Avena-Bustillos RJ, Wood DF, Williams TG, McHugh TH.Bilbao-Sáinz C, et al.J Agric Food Chem. 2010 Nov 24;58(22):11932-8. doi: 10.1021/jf102341r. Epub 2010 Oct 26.J Agric Food Chem. 2010.PMID:20977191
- Ultrasonic energy input influence οn the production of sub-micron o/w emulsions containing whey protein and common stabilizers.Kaltsa O, Michon C, Yanniotis S, Mandala I.Kaltsa O, et al.Ultrason Sonochem. 2013 May;20(3):881-91. doi: 10.1016/j.ultsonch.2012.11.011. Epub 2012 Nov 28.Ultrason Sonochem. 2013.PMID:23266492
- Selective retardation of perfume oil evaporation from oil-in-water emulsions stabilized by either surfactant or nanoparticles.Binks BP, Fletcher PD, Holt BL, Beaussoubre P, Wong K.Binks BP, et al.Langmuir. 2010 Dec 7;26(23):18024-30. doi: 10.1021/la103700g. Epub 2010 Nov 10.Langmuir. 2010.PMID:21067125
- Design and production of nanoparticles formulated from nano-emulsion templates-a review.Anton N, Benoit JP, Saulnier P.Anton N, et al.J Control Release. 2008 Jun 24;128(3):185-99. doi: 10.1016/j.jconrel.2008.02.007. Epub 2008 Feb 23.J Control Release. 2008.PMID:18374443Review.
- Ultrasonic and homogenization: An overview of the preparation of an edible protein-polysaccharide complex emulsion.Qayum A, Rashid A, Liang Q, Wu Y, Cheng Y, Kang L, Liu Y, Zhou C, Hussain M, Ren X, Ashokkumar M, Ma H.Qayum A, et al.Compr Rev Food Sci Food Saf. 2023 Nov;22(6):4242-4281. doi: 10.1111/1541-4337.13221. Epub 2023 Sep 21.Compr Rev Food Sci Food Saf. 2023.PMID:37732485Review.
Cited by
- An Experimental Study on Enhancing Microbial Desulfurization of Sulfide Ores Using Ultrasonic Treatment.Pan W, Yi R, Liao Z, Yang L.Pan W, et al.Materials (Basel). 2022 Apr 2;15(7):2620. doi: 10.3390/ma15072620.Materials (Basel). 2022.PMID:35407956Free PMC article.
- Ultrasound-assisted production and optimization of mini-emulsions in a microfluidic chip in continuous-flow.Nieves E, Vite G, Kozina A, Olguin LF.Nieves E, et al.Ultrason Sonochem. 2021 Jun;74:105556. doi: 10.1016/j.ultsonch.2021.105556. Epub 2021 Apr 15.Ultrason Sonochem. 2021.PMID:33915482Free PMC article.
- Development, optimization and in vitro evaluation of oxaliplatin loaded nanoparticles in non-small cell lung cancer.Esim O, Bakirhan NK, Yildirim N, Sarper M, Savaser A, Ozkan SA, Ozkan Y.Esim O, et al.Daru. 2020 Dec;28(2):673-684. doi: 10.1007/s40199-020-00374-5. Epub 2020 Oct 22.Daru. 2020.PMID:33089432Free PMC article.
- Elicitation of Novel Trichogenic-Lipid Nanoemulsion Signaling Resistance Against Pearl Millet Downy Mildew Disease.Nandini B, Puttaswamy H, H S P, Adhikari S, Jogaiah S, Nagaraja G.Nandini B, et al.Biomolecules. 2019 Dec 23;10(1):25. doi: 10.3390/biom10010025.Biomolecules. 2019.PMID:31878099Free PMC article.
- Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide.Yen CC, Chen YC, Wu MT, Wang CC, Wu YT.Yen CC, et al.Int J Nanomedicine. 2018 Jan 31;13:669-680. doi: 10.2147/IJN.S154824. eCollection 2018.Int J Nanomedicine. 2018.PMID:29440893Free PMC article.
Publication types
MeSH terms
Substances
Related information
LinkOut - more resources
Full Text Sources
Other Literature Sources