Epidemiology of staphylococcal resistance
- PMID:17712743
- DOI: 10.1086/519473
Epidemiology of staphylococcal resistance
Abstract
An understanding of the prevalence of resistant Staphylococcus aureus and the risk factors for infection with resistant isolates is essential to help clinicians choose appropriate antibiotic therapy. Selection pressure due to prior and inappropriate antibiotic use of any kind seems to be the main driving force behind the increasing rates of multidrug resistance in methicillin-resistant S. aureus (MRSA) strains. Resistance to glycopeptide antibiotics in MRSA has also emerged in recent years, along with increased use of vancomycin to treat serious infections due to MRSA. Infections due to MRSA are associated with significantly increased morbidity, mortality, length of hospital stay, and costs, compared with infections due to methicillin-susceptible S. aureus, despite adjustment for disease severity and initially appropriate antibiotic treatment. Improvements in the preparation and dissemination of antibiograms, along with adequate public reporting of MRSA trends, are needed to address the challenge of choosing appropriate initial antibiotic treatment for MRSA infections.
Similar articles
- Microbiology of antibiotic resistance in Staphylococcus aureus.Appelbaum PC.Appelbaum PC.Clin Infect Dis. 2007 Sep 15;45 Suppl 3:S165-70. doi: 10.1086/519474.Clin Infect Dis. 2007.PMID:17712742Review.
- Increasing antibiotic resistance among methicillin-resistant Staphylococcus aureus strains.Sakoulas G, Moellering RC Jr.Sakoulas G, et al.Clin Infect Dis. 2008 Jun 1;46 Suppl 5:S360-7. doi: 10.1086/533592.Clin Infect Dis. 2008.PMID:18462091Review.
- Increasing prevalence of methicillin resistance in serious ocular infections caused by Staphylococcus aureus in the United States: 2000 to 2005.Asbell PA, Sahm DF, Shaw M, Draghi DC, Brown NP.Asbell PA, et al.J Cataract Refract Surg. 2008 May;34(5):814-8. doi: 10.1016/j.jcrs.2008.01.016.J Cataract Refract Surg. 2008.PMID:18471638
- Risk factors associated with methicillin-resistant Staphylococcus aureus infection in patients admitted to the ED.Viallon A, Marjollet O, Berthelot P, Carricajo A, Guyomarc'h S, Robert F, Zeni F, Bertrand JC.Viallon A, et al.Am J Emerg Med. 2007 Oct;25(8):880-6. doi: 10.1016/j.ajem.2007.01.013.Am J Emerg Med. 2007.PMID:17920971
- Reduced glycopeptide susceptibility in methicillin-resistant Staphylococcus aureus (MRSA).Appelbaum PC.Appelbaum PC.Int J Antimicrob Agents. 2007 Nov;30(5):398-408. doi: 10.1016/j.ijantimicag.2007.07.011. Epub 2007 Sep 20.Int J Antimicrob Agents. 2007.PMID:17888634Review.
Cited by
- MRSA virulence and spread.Otto M.Otto M.Cell Microbiol. 2012 Oct;14(10):1513-21. doi: 10.1111/j.1462-5822.2012.01832.x. Epub 2012 Jul 17.Cell Microbiol. 2012.PMID:22747834Free PMC article.Review.
- Degree of Contamination of Gutta-Percha Points byStaphylococcus aureus (MRSA/MSSA) Strains.Teles AM, Pina C, Cardoso IL, Tramontana A, Cardoso M, Duarte AS, Bartolomeu M, Noites R.Teles AM, et al.Int J Mol Sci. 2024 Aug 6;25(16):8566. doi: 10.3390/ijms25168566.Int J Mol Sci. 2024.PMID:39201252Free PMC article.
- Efficacy ofCordyceps militaris Extracts against Some Skin Pathogenic Bacteria and Antioxidant Activity.Eiamthaworn K, Kaewkod T, Bovonsombut S, Tragoolpua Y.Eiamthaworn K, et al.J Fungi (Basel). 2022 Mar 22;8(4):327. doi: 10.3390/jof8040327.J Fungi (Basel). 2022.PMID:35448557Free PMC article.
- Clinically Approved Drugs Inhibit theStaphylococcus aureus Multidrug NorA Efflux Pump and Reduce Biofilm Formation.Zimmermann S, Klinger-Strobel M, Bohnert JA, Wendler S, Rödel J, Pletz MW, Löffler B, Tuchscherr L.Zimmermann S, et al.Front Microbiol. 2019 Dec 3;10:2762. doi: 10.3389/fmicb.2019.02762. eCollection 2019.Front Microbiol. 2019.PMID:31849901Free PMC article.
- 11C-Para-aminobenzoic acid PET imaging of S. aureus and MRSA infection in preclinical models and humans.Ordonez AA, Parker MF, Miller RJ, Plyku D, Ruiz-Bedoya CA, Tucker EW, Luu JM, Dikeman DA, Lesniak WG, Holt DP, Dannals RF, Miller LS, Rowe SP, Wilson DM, Jain SK.Ordonez AA, et al.JCI Insight. 2022 Jan 11;7(1):e154117. doi: 10.1172/jci.insight.154117.JCI Insight. 2022.PMID:35014627Free PMC article.
Publication types
MeSH terms
Substances
Related information
LinkOut - more resources
Full Text Sources
Medical