Percutaneous core biopsy for renal masses: indications, accuracy and results
- PMID:17698122
- DOI: 10.1016/j.juro.2007.05.155
Percutaneous core biopsy for renal masses: indications, accuracy and results
Abstract
Purpose: We evaluated the results, accuracy and clinical incidence of our standard procedure of percutaneous biopsy for solid renal masses.
Materials and methods: From March 1999 to April 2005, 119 percutaneous core biopsies of renal masses were performed. Biopsies were proposed when there was no formal evidence for a carcinoma diagnosis on computerized tomography.
Results: Benign lesions were diagnosed in 24 biopsies (20.1%), including oncocytoma in 13, angiomyolipoma in 5 and chronic pyelonephritis in 5. Malignancy was identified in 70 biopsies (58.8%), including 57 renal carcinomas (conventional renal cell in 41, papillary in 12 and chromophobe in 4), 4 transitional cell carcinomas, 8 metastases and 1 lymphoma. For 25 biopsies (21%) no accurate diagnosis was possible, including 12 that showed inflammatory tissue and 13 with normal or necrotic tissue. These inconclusive biopsies prompted repeat biopsy in 13 patients, in whom a total of 11 malignant lesions were diagnosed. A total of 64 nephrectomies were performed with a biopsy accuracy for histopathological tumor type and Fuhrman nuclear grade of 86% and 46%, respectively. A period of watchful waiting was proposed for 31 patients (34.2%) and no renal malignancies were found. Computerized tomography showed stabilization or disappearance of the initial renal mass.
Conclusions: Percutaneous renal tumor biopsies are safe, cost-effective and often conclusive for an acute histological diagnosis. This procedure could be decisive for choosing the optimal treatment, particularly to avoid nephrectomy for benign lesions. Biopsies should not be considered a routine procedure but they could be indicated when there is a lack of radiological evidence in elective patients.
Similar articles
- Percutaneous core biopsy of small renal mass lesions: a diagnostic tool to better stratify patients for surgical intervention.Menogue SR, O'Brien BA, Brown AL, Cohen RJ.Menogue SR, et al.BJU Int. 2013 Apr;111(4 Pt B):E146-51. doi: 10.1111/j.1464-410X.2012.11384.x. Epub 2012 Jul 13.BJU Int. 2013.PMID:22805186
- The value of preoperative needle core biopsy for diagnosing benign lesions among small, incidentally detected renal masses.Shannon BA, Cohen RJ, de Bruto H, Davies RJ.Shannon BA, et al.J Urol. 2008 Oct;180(4):1257-61; discussion 1261. doi: 10.1016/j.juro.2008.06.030. Epub 2008 Aug 15.J Urol. 2008.PMID:18707712
- [Diagnostic value of percutaneous biopsy of the renal masses. 73 cases].Daniel L, Barriol D, Lechevallier E, André M, De Fromont M, Charafe E, Coulange C, Pellissier J.Daniel L, et al.Ann Pathol. 2000 Mar;20(2):119-23.Ann Pathol. 2000.PMID:10740006French.
- The current role of percutaneous needle biopsies of renal tumours.Volpe A, Terrone C, Scarpa RM.Volpe A, et al.Arch Ital Urol Androl. 2009 Jun;81(2):107-12.Arch Ital Urol Androl. 2009.PMID:19760866Review.
- Renal biopsies for small renal masses. For whom, when and how.Stakhovsky O, Sanchez-Salas R, Barret E, Yap SA, Finelli A, Rozet F, Galiano M, Lenoir S, Strauss C, Validire P, Cathelineau X.Stakhovsky O, et al.Arch Esp Urol. 2013 Jan-Feb;66(1):4-15.Arch Esp Urol. 2013.PMID:23406796Review.
Cited by
- Three-Tesla dynamic contrast-enhanced MRI: a critical assessment of its use for differentiation of renal lesion subtypes.Sevcenco S, Ponhold L, Javor D, Kuehhas FE, Mauermann J, Miernik A, Schoenthaler M, Baltzer PA.Sevcenco S, et al.World J Urol. 2014 Feb;32(1):215-20. doi: 10.1007/s00345-013-1177-1. Epub 2013 Oct 9.World J Urol. 2014.PMID:24105251
- R.E.N.A.L. Nephrometry Score: A Preoperative Risk Factor Predicting the Fuhrman Grade of Clear-Cell Renal Carcinoma.Chen SH, Wu YP, Li XD, Lin T, Guo QY, Chen YH, Huang JB, Wei Y, Xue XY, Zheng QS, Xu N.Chen SH, et al.J Cancer. 2017 Oct 17;8(18):3725-3732. doi: 10.7150/jca.21189. eCollection 2017.J Cancer. 2017.PMID:29151960Free PMC article.
- Accuracy, safety, and diagnostic prediction of percutaneous renal mass biopsy and subsequent changes in treatment.Chen S, Chen Y, Li J, Zu Q, Yang Z, Hu M, Ye L.Chen S, et al.Wideochir Inne Tech Maloinwazyjne. 2024 Mar;19(1):113-121. doi: 10.5114/wiitm.2024.135411. Epub 2024 Feb 14.Wideochir Inne Tech Maloinwazyjne. 2024.PMID:38974758Free PMC article.
- Percutaneous biopsy of primary tumor in metastatic renal cell carcinoma to predict high risk pathological features: comparison with nephrectomy assessment.Abel EJ, Culp SH, Matin SF, Tamboli P, Wallace MJ, Jonasch E, Tannir NM, Wood CG.Abel EJ, et al.J Urol. 2010 Nov;184(5):1877-81. doi: 10.1016/j.juro.2010.06.105. Epub 2010 Sep 17.J Urol. 2010.PMID:20850148Free PMC article.
- Histological characterisation of small renal masses and incidence of silent renal masses.Almenar Medina S, Calatrava Fons A.Almenar Medina S, et al.Adv Urol. 2008;2008:758073. doi: 10.1155/2008/758073. Epub 2008 Nov 4.Adv Urol. 2008.PMID:19009035Free PMC article.
MeSH terms
Related information
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous