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.2007 Jul;22(7):1030-4.
doi: 10.1007/s11606-007-0141-4. Epub 2007 Mar 7.

Bioidentical hormones for menopausal hormone therapy: variation on a theme

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Bioidentical hormones for menopausal hormone therapy: variation on a theme

Adriane Fugh-Berman et al. J Gen Intern Med.2007 Jul.

Abstract

Background: Progesterone creams and natural or bioidentical compounded estrogen preparations are being promoted to consumers as safe alternatives to conventional menopausal hormone therapy and as health-promoting tonics. No reliable data support these claims.

Safety: Natural hormones, including estradiol, estriol, estrone, and progesterone, can be expected to have the same adverse event profile as conventional menopausal hormone regimens.

Salivary hormone tests: Salivary tests may be used to persuade asymptomatic consumers to use hormones (or symptomatic patients to use higher doses than those needed to mitigate symptoms), a practice that can be expected to result in adverse events.

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