Review
doi: 10.1101/sqb.2006.71.006.Architecture of a microRNA-controlled gene regulatory network that diversifies neuronal cell fates
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- PMID:17381295
- DOI: 10.1101/sqb.2006.71.006
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Review
Architecture of a microRNA-controlled gene regulatory network that diversifies neuronal cell fates
O Hobert. Cold Spring Harb Symp Quant Biol.2006.
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Abstract
Individual cell types are defined by the expression of specific gene batteries. Regulatory networks that control cell-type-specific gene expression programs in the nervous system are only beginning to be understood. This paper summarizes a complex gene regulatory network, composed of several transcription factors and microRNAs (miRNAs), that controls neuronal subclass specification in the nervous system of the nematode Caenorhabditis elegans.
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