doi: 10.3201/eid1301.060810.
Rabies encephalitis in malaria-endemic area, Malawi, Africa
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- PMID:17370529
- PMCID: PMC2725806
- DOI: 10.3201/eid1301.060810
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Rabies encephalitis in malaria-endemic area, Malawi, Africa
Macpherson Mallewa et al. Emerg Infect Dis.2007 Jan.
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Abstract
In a malaria-endemic area of Africa, rabies was an important cause of fatal central nervous system infection, responsible for 14 (10.5%) of 133 cases. Four patients had unusual clinical manifestations, and rabies was only diagnosed postmortem. Three (11.5%) of 26 fatal cases originally attributed to cerebral malaria were due to rabies.
Figures
Phylogenetic tree, based on 400 nucleotides of the nucleoprotein gene (10), showing the relationship between rabies virus isolates in this study from humans (inboldface) and animals (underlined ), and other representative isolates; GenBank accession nos. are in brackets. Bootstrap values >70% are considered significant and are included within the figure. The Africa 1, 2, 3, and 4 genotypes are within rabies virus genotype 1 (13).
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References
- World Health Organization. Management of severe malaria. Geneva: The Organization; 2000.
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