Gadolinium deposition in nephrogenic fibrosing dermopathy
- PMID:17109993
- DOI: 10.1016/j.jaad.2006.10.048
Gadolinium deposition in nephrogenic fibrosing dermopathy
Abstract
There is growing recognition of the association between the use of gadolinium-containing radiocontrast agents for magnetic resonance imaging and the serious dermal and systemic disease nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis (NFD/NSF). The pathogenesis of this entity remains unclear; however, our recent observations suggest a likely mechanism for the initial dermal manifestations of this gadolinium toxicity.
Comment in
- Gadolinium is not deposited in the skin of patients with normal renal function after exposure to gadolinium-based contrast agents.Boyd AS, Sanyal S, Abraham JL.Boyd AS, et al.J Am Acad Dermatol. 2008 Aug;59(2):356-8. doi: 10.1016/j.jaad.2008.01.025.J Am Acad Dermatol. 2008.PMID:18638638No abstract available.
Similar articles
- Gadolinium is detectable within the tissue of patients with nephrogenic systemic fibrosis.High WA, Ayers RA, Chandler J, Zito G, Cowper SE.High WA, et al.J Am Acad Dermatol. 2007 Jan;56(1):21-6. doi: 10.1016/j.jaad.2006.10.047. Epub 2006 Nov 9.J Am Acad Dermatol. 2007.PMID:17097388
- Gadolinium-induced nephrogenic systemic fibrosis is associated with insoluble Gd deposits in tissues: in vivo transmetallation confirmed by microanalysis.Thakral C, Abraham JL.Thakral C, et al.J Cutan Pathol. 2009 Dec;36(12):1244-54. doi: 10.1111/j.1600-0560.2009.01283.x. Epub 2009 Jul 7.J Cutan Pathol. 2009.PMID:19602073
- Gadolinium-associated nephrogenic systemic fibrosis: the need for nephrologists' awareness.Canavese C, Mereu MC, Aime S, Lazzarich E, Fenoglio R, Quaglia M, Stratta P.Canavese C, et al.J Nephrol. 2008 May-Jun;21(3):324-36.J Nephrol. 2008.PMID:18587720Review.
- Nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis.Hamilton-Persaud K, Ezell LD, Macklin JG.Hamilton-Persaud K, et al.Nephrol Nurs J. 2007 May-Jun;34(3):283-7; quiz 288.Nephrol Nurs J. 2007.PMID:17644872Review.
- Time-dependent decrement of dermal gadolinium deposits and significant improvement of skin symptoms in a patient with nephrogenic systemic fibrosis after temporary renal failure.Schäd SG, Heitland P, Kühn-Velten WN, Gross GE, Jonas L.Schäd SG, et al.J Cutan Pathol. 2013 Nov;40(11):935-44. doi: 10.1111/cup.12214. Epub 2013 Sep 16.J Cutan Pathol. 2013.PMID:24102613
Cited by
- Nephrogenic Systemic Fibrosis as a Complication after Gadolinium-Containing Contrast Agents: A Rapid Review.Lange S, Mędrzycka-Dąbrowska W, Zorena K, Dąbrowski S, Ślęzak D, Malecka-Dubiela A, Rutkowski P.Lange S, et al.Int J Environ Res Public Health. 2021 Mar 15;18(6):3000. doi: 10.3390/ijerph18063000.Int J Environ Res Public Health. 2021.PMID:33804005Free PMC article.Review.
- Albumin-based nanoparticles as contrast medium for MRI: vascular imaging, tissue and cell interactions, and pharmacokinetics of second-generation nanoparticles.Wallnöfer EA, Thurner GC, Kremser C, Talasz H, Stollenwerk MM, Helbok A, Klammsteiner N, Albrecht-Schgoer K, Dietrich H, Jaschke W, Debbage P.Wallnöfer EA, et al.Histochem Cell Biol. 2021 Jan;155(1):19-73. doi: 10.1007/s00418-020-01919-0. Epub 2020 Oct 11.Histochem Cell Biol. 2021.PMID:33040183
- Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics.Villaraza AJ, Bumb A, Brechbiel MW.Villaraza AJ, et al.Chem Rev. 2010 May 12;110(5):2921-59. doi: 10.1021/cr900232t.Chem Rev. 2010.PMID:20067234Free PMC article.Review.No abstract available.
- Gadolinium and nephrogenic systemic fibrosis: an update.Weller A, Barber JL, Olsen OE.Weller A, et al.Pediatr Nephrol. 2014 Oct;29(10):1927-37. doi: 10.1007/s00467-013-2636-z. Epub 2013 Oct 22.Pediatr Nephrol. 2014.PMID:24146299Review.
- Application of magnetic resonance urography in diagnosis of congenital urogenital anomalies in children.Payabvash S, Kajbafzadeh AM, Saeedi P, Sadeghi Z, Elmi A, Mehdizadeh M.Payabvash S, et al.Pediatr Surg Int. 2008 Sep;24(9):979-86. doi: 10.1007/s00383-008-2196-7. Epub 2008 Jul 31.Pediatr Surg Int. 2008.PMID:18668256
Publication types
MeSH terms
Substances
Related information
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical