Can open-source R&D reinvigorate drug research?
- PMID:16915233
- DOI: 10.1038/nrd2131
Can open-source R&D reinvigorate drug research?
Abstract
The low number of novel therapeutics approved by the US FDA in recent years continues to cause great concern about productivity and declining innovation. Can open-source drug research and development, using principles pioneered by the highly successful open-source software movement, help revive the industry?
Similar articles
- Trends in development and approval times for new therapeutics in the United States.Reichert JM.Reichert JM.Nat Rev Drug Discov. 2003 Sep;2(9):695-702. doi: 10.1038/nrd1178.Nat Rev Drug Discov. 2003.PMID:12951576Review.
- The state of innovation in drug development.Kola I.Kola I.Clin Pharmacol Ther. 2008 Feb;83(2):227-30. doi: 10.1038/sj.clpt.6100479.Clin Pharmacol Ther. 2008.PMID:18202690
- Trends in antimicrobial drug development: implications for the future.Spellberg B, Powers JH, Brass EP, Miller LG, Edwards JE Jr.Spellberg B, et al.Clin Infect Dis. 2004 May 1;38(9):1279-86. doi: 10.1086/420937. Epub 2004 Apr 14.Clin Infect Dis. 2004.PMID:15127341
- The critical path to medical innovation.Williams D.Williams D.Med Device Technol. 2004 Jun;15(5):8-10.Med Device Technol. 2004.PMID:15285478
- Progress in standards for reporting omics data.Taylor CF.Taylor CF.Curr Opin Drug Discov Devel. 2007 May;10(3):254-63.Curr Opin Drug Discov Devel. 2007.PMID:17554851Review.
Cited by
- Functional and Material Properties in Nanocatalyst Design: A Data Handling and Sharing Problem.Lach D, Zhdan U, Smolinski A, Polanski J.Lach D, et al.Int J Mol Sci. 2021 May 13;22(10):5176. doi: 10.3390/ijms22105176.Int J Mol Sci. 2021.PMID:34068386Free PMC article.Review.
- Accelerating Therapeutics for Opportunities in Medicine: A Paradigm Shift in Drug Discovery.Hinkson IV, Madej B, Stahlberg EA.Hinkson IV, et al.Front Pharmacol. 2020 Jun 30;11:770. doi: 10.3389/fphar.2020.00770. eCollection 2020.Front Pharmacol. 2020.PMID:32694991Free PMC article.
- Crowdsourcing in medical research: concepts and applications.Tucker JD, Day S, Tang W, Bayus B.Tucker JD, et al.PeerJ. 2019 Apr 12;7:e6762. doi: 10.7717/peerj.6762. eCollection 2019.PeerJ. 2019.PMID:30997295Free PMC article.
- Common characteristics of open source software development and applicability for drug discovery: a systematic review.Ardal C, Alstadsæter A, Røttingen JA.Ardal C, et al.Health Res Policy Syst. 2011 Sep 28;9:36. doi: 10.1186/1478-4505-9-36.Health Res Policy Syst. 2011.PMID:21955914Free PMC article.
- More medicines for neglected and emerging infectious diseases.Radisch J.Radisch J.Bull World Health Organ. 2007 Aug;85(8):572. doi: 10.2471/blt.07.045690.Bull World Health Organ. 2007.PMID:17768509Free PMC article.No abstract available.
Publication types
MeSH terms
Related information
LinkOut - more resources
Full Text Sources