Cognitive effects of diarrhea, malnutrition, and Entamoeba histolytica infection on school age children in Dhaka, Bangladesh
- PMID:16525109
Cognitive effects of diarrhea, malnutrition, and Entamoeba histolytica infection on school age children in Dhaka, Bangladesh
Abstract
Cognitive function was assessed in 191 Bangladeshi children 6-9 years of age using verbal and nonverbal tests. These scores were added to a health surveillance database that was compiled over the four previous years that includes incidence of diarrhea and Entamoeba histolytica infection and nutritional status. The associations of diarrhea, malnutrition, and social factors with cognitive scores were analyzed statistically, and associations between diarrhea and test scores were controlled for the influence of social factors. Cognitive scores were negatively associated with stunting during school age, as well as the height-for-age and weight-for-age scores at study enrollment. Incidence of diarrhea was associated with nonverbal test scores before, but not after, controlling for socioeconomic factors. Generally E. histolytica infection was not found to independently influence scores, except that E. histolytica-associated dysentery was associated with lower test scores while dysentery of any etiology was not. Thus, malnutrition during the school age years, but not diarrhea or E. histolytica infection, was associated with a lower level of cognitive functioning. This suggested that intervention during school age years may be able to mitigate the cognitive deficiencies associated with malnutrition.
Similar articles
- Correlation of interferon-gamma production by peripheral blood mononuclear cells with childhood malnutrition and susceptibility to amebiasis.Haque R, Mondal D, Shu J, Roy S, Kabir M, Davis AN, Duggal P, Petri WA Jr.Haque R, et al.Am J Trop Med Hyg. 2007 Feb;76(2):340-4.Am J Trop Med Hyg. 2007.PMID:17297046
- Epidemiologic and clinical characteristics of acute diarrhea with emphasis on Entamoeba histolytica infections in preschool children in an urban slum of Dhaka, Bangladesh.Haque R, Mondal D, Kirkpatrick BD, Akther S, Farr BM, Sack RB, Petri WA Jr.Haque R, et al.Am J Trop Med Hyg. 2003 Oct;69(4):398-405.Am J Trop Med Hyg. 2003.PMID:14640500
- Entamoeba histolytica-associated diarrheal illness is negatively associated with the growth of preschool children: evidence from a prospective study.Mondal D, Petri WA Jr, Sack RB, Kirkpatrick BD, Haque R.Mondal D, et al.Trans R Soc Trop Med Hyg. 2006 Nov;100(11):1032-8. doi: 10.1016/j.trstmh.2005.12.012. Epub 2006 May 30.Trans R Soc Trop Med Hyg. 2006.PMID:16730764
- Association of malnutrition with amebiasis.Petri WA Jr, Mondal D, Peterson KM, Duggal P, Haque R.Petri WA Jr, et al.Nutr Rev. 2009 Nov;67 Suppl 2:S207-15. doi: 10.1111/j.1753-4887.2009.00242.x.Nutr Rev. 2009.PMID:19906225Review.
- The association between stunting and psychosocial development among preschool children: a study using the South African Birth to Twenty cohort data.Casale D, Desmond C, Richter L.Casale D, et al.Child Care Health Dev. 2014 Nov;40(6):900-10. doi: 10.1111/cch.12143. Epub 2014 May 8.Child Care Health Dev. 2014.PMID:24807234Review.
Cited by
- Epidemiology and control of human gastrointestinal parasites in children.Harhay MO, Horton J, Olliaro PL.Harhay MO, et al.Expert Rev Anti Infect Ther. 2010 Feb;8(2):219-34. doi: 10.1586/eri.09.119.Expert Rev Anti Infect Ther. 2010.PMID:20109051Free PMC article.Review.
- Linear Growth Faltering Is Associated with Subsequent Adverse Child Cognitive Developmental Outcomes in the Democratic Republic of the Congo (REDUCE Program).George CM, Perin J, Kuhl J, Williams C, Coglianese N, Thomas ED, Bauler S, François R, Ng A, Kang Y, Presence AS, Jean Claude BR, Tofail F, Mirindi P, Cirhuza LB.George CM, et al.Am J Trop Med Hyg. 2021 Nov 1;106(1):356-360. doi: 10.4269/ajtmh.21-0502.Am J Trop Med Hyg. 2021.PMID:34724633Free PMC article.
- Malnutrition and gastrointestinal and respiratory infections in children: a public health problem.Rodríguez L, Cervantes E, Ortiz R.Rodríguez L, et al.Int J Environ Res Public Health. 2011 Apr;8(4):1174-205. doi: 10.3390/ijerph8041174. Epub 2011 Apr 18.Int J Environ Res Public Health. 2011.PMID:21695035Free PMC article.Review.
- Developmental trends in early childhood and their predictors from an Indian birth cohort.Koshy B, Srinivasan M, Bose A, John S, Mohan VR, Roshan R, Ramanujam K, Kang G.Koshy B, et al.BMC Public Health. 2021 Jun 6;21(1):1083. doi: 10.1186/s12889-021-11147-3.BMC Public Health. 2021.PMID:34090391Free PMC article.
- An ex-vivo human intestinal model to study Entamoeba histolytica pathogenesis.Bansal D, Ave P, Kerneis S, Frileux P, Boché O, Baglin AC, Dubost G, Leguern AS, Prevost MC, Bracha R, Mirelman D, Guillén N, Labruyère E.Bansal D, et al.PLoS Negl Trop Dis. 2009 Nov 17;3(11):e551. doi: 10.1371/journal.pntd.0000551.PLoS Negl Trop Dis. 2009.PMID:19936071Free PMC article.
Publication types
MeSH terms
Related information
Grants and funding
LinkOut - more resources
Medical