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.2006 Jan 18;128(2):426-7.
doi: 10.1021/ja0574567.

Total synthesis of UCS1025A

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Total synthesis of UCS1025A

Tristan H Lambert et al. J Am Chem Soc..

Abstract

The enantioselective total synthesis of the telomerase inhibitor UCS1025A has been accomplished. The key transformation involves a remarkable boron Reformatsky coupling of iodolactone 13 and aldehyde 17.

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