Review
doi: 10.1016/j.yfrne.2005.10.003. Epub 2005 Nov 23.Pubertal hormones organize the adolescent brain and behavior
Affiliations
- PMID:16309736
- DOI: 10.1016/j.yfrne.2005.10.003
Item in Clipboard
Review
Pubertal hormones organize the adolescent brain and behavior
Cheryl L Sisk et al. Front Neuroendocrinol.2005 Oct-Dec.
Display options
Format
Display options
Format
Abstract
Maturation of the reproductive system during puberty results in elevated levels of gonadal steroid hormones. These hormones sculpt neural circuits during adolescence, a time of dramatic rewiring of the nervous system. Here, we review the evidence that steroid-dependent organization of the adolescent brain programs a variety of adult behaviors in animals and humans. Converging lines of evidence indicate that adolescence may be a sensitive period for steroid-dependent brain organization and that variation in the timing of interactions between the hormones of puberty and the adolescent brain leads to individual differences in adult behavior and risk of sex-biased psychopathologies.
Similar articles
- The neural basis of puberty and adolescence.Sisk CL, Foster DL.Sisk CL, et al.Nat Neurosci. 2004 Oct;7(10):1040-7. doi: 10.1038/nn1326.Nat Neurosci. 2004.PMID:15452575Review.
- Back to the future: The organizational-activational hypothesis adapted to puberty and adolescence.Schulz KM, Molenda-Figueira HA, Sisk CL.Schulz KM, et al.Horm Behav. 2009 May;55(5):597-604. doi: 10.1016/j.yhbeh.2009.03.010.Horm Behav. 2009.PMID:19446076Free PMC article.Review.
- Timing of peripubertal steroid exposure predicts visuospatial cognition in men: Evidence from three samples.Shirazi TN, Self H, Cantor J, Dawood K, Cárdenas R, Rosenfield K, Ortiz T, Carré J, McDaniel MA, Blanchard R, Balasubramanian R, Delaney A, Crowley W, Breedlove SM, Puts D.Shirazi TN, et al.Horm Behav. 2020 May;121:104712. doi: 10.1016/j.yhbeh.2020.104712. Epub 2020 Feb 18.Horm Behav. 2020.PMID:32059854Free PMC article.
- Sexual maturation and differentiation: the role of the gonadal steroids.McEwen BS.McEwen BS.Prog Brain Res. 1978;48:291-308. doi: 10.1016/S0079-6123(08)61030-4.Prog Brain Res. 1978.PMID:85313Review.No abstract available.
- Puberty: a period of both organizational and activational effects of steroid hormones on neurobehavioural development.Romeo RD.Romeo RD.J Neuroendocrinol. 2003 Dec;15(12):1185-92. doi: 10.1111/j.1365-2826.2003.01106.x.J Neuroendocrinol. 2003.PMID:14636181Review.
Cited by
- Focus on: Comorbid mental health disorders.Anthenelli RM.Anthenelli RM.Alcohol Res Health. 2010;33(1-2):109-17.Alcohol Res Health. 2010.PMID:23579941Free PMC article.Review.
- Body mass index and other anthropometric variables in children with sickle cell anaemia.Odetunde OI, Chinawa JM, Achigbu KI, Achigbu EO.Odetunde OI, et al.Pak J Med Sci. 2016 Mar-Apr;32(2):341-6. doi: 10.12669/pjms.322.9046.Pak J Med Sci. 2016.PMID:27182236Free PMC article.
- Framework for sex differences in adolescent neurobiology: a focus on cannabinoids.Viveros MP, Marco EM, López-Gallardo M, Garcia-Segura LM, Wagner EJ.Viveros MP, et al.Neurosci Biobehav Rev. 2011 Aug;35(8):1740-51. doi: 10.1016/j.neubiorev.2010.09.005. Epub 2010 Sep 30.Neurosci Biobehav Rev. 2011.PMID:20869396Free PMC article.Review.
- Brief, computerized inhibitory control training to leverage adolescent neural plasticity: A pilot effectiveness trial.Beauchamp KG, Shaffer KA, Fisher PA, Berkman ET.Beauchamp KG, et al.Appl Neuropsychol Child. 2019 Oct-Dec;8(4):366-382. doi: 10.1080/21622965.2018.1495567. Epub 2018 Sep 28.Appl Neuropsychol Child. 2019.PMID:30265572Free PMC article.Clinical Trial.
- Sensitivity to ethanol and other hedonic stimuli in an animal model of adolescence: implications for prevention science?Spear LP, Varlinskaya EI.Spear LP, et al.Dev Psychobiol. 2010 Apr;52(3):236-43. doi: 10.1002/dev.20457.Dev Psychobiol. 2010.PMID:20222058Free PMC article.Review.
Publication types
MeSH terms
Substances
Related information
Grants and funding
LinkOut - more resources
Full Text Sources
Medical