Review
doi: 10.1007/s00018-004-4257-y.The SARS-CoV S glycoprotein
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- PMID:15526150
- PMCID: PMC7079772
- DOI: 10.1007/s00018-004-4257-y
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Review
The SARS-CoV S glycoprotein
X Xiao et al. Cell Mol Life Sci.2004 Oct.
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Abstract
The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. Recent rapid advances in our knowledge of the structure and function of this protein have lead to the development of a number of candidate vaccine immunogens and SARS-CoV entry inhibitors.
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