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doi: 10.1016/j.chembiol.2004.07.002.Ribozyme diagnostics comes of age
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- PMID:15271347
- DOI: 10.1016/j.chembiol.2004.07.002
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Comment
Ribozyme diagnostics comes of age
John J Rossi. Chem Biol.2004 Jul.
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Abstract
Biosensing ribozymes could soon be used to diagnose viral infection. The Kossen group from Sirna Therapeutics have developed a sensitive, high-throughput means of screening for hepatitis C virus, using their target activated half-ribozyme technology, as reported in the June issue of Chemistry & Biology.
Comment on
- High-throughput ribozyme-based assays for detection of viral nucleic acids.Kossen K, Vaish NK, Jadhav VR, Pasko C, Wang H, Jenison R, McSwiggen JA, Polisky B, Seiwert SD.Kossen K, et al.Chem Biol. 2004 Jun;11(6):807-15. doi: 10.1016/j.chembiol.2004.03.029.Chem Biol. 2004.PMID:15217614
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