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.1993 Mar;3(3):69-72.
doi: 10.1016/0962-8924(93)90065-9.

Potocytosis of small molecules and ions by caveolae

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Potocytosis of small molecules and ions by caveolae

R G Anderson. Trends Cell Biol.1993 Mar.

Abstract

Potocytosis is an endocytic process for concentrating and taking up small molecules and ions. The vehicle for internalization is the caveolae, a membrane specialization that has previously been implicated in membrane internalization. Within closed caveolae, the glycosylphosphatidylinositol-anchored class of membrane proteins generate high concentrations of small molecules or ions either by releasing receptor-bound species, by enzymatically converting abundant extracellular molecules, or by releasing them from a sequestered, soluble carrier protein. This pathway may also be involved in novel signal-transducing devices.

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