Potocytosis of small molecules and ions by caveolae
- PMID:14731772
- DOI: 10.1016/0962-8924(93)90065-9
Potocytosis of small molecules and ions by caveolae
Abstract
Potocytosis is an endocytic process for concentrating and taking up small molecules and ions. The vehicle for internalization is the caveolae, a membrane specialization that has previously been implicated in membrane internalization. Within closed caveolae, the glycosylphosphatidylinositol-anchored class of membrane proteins generate high concentrations of small molecules or ions either by releasing receptor-bound species, by enzymatically converting abundant extracellular molecules, or by releasing them from a sequestered, soluble carrier protein. This pathway may also be involved in novel signal-transducing devices.
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