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.1962 Oct 12;138(3537):143-4.
doi: 10.1126/science.138.3537.143.

Experimental morphine addiction: method for automatic intravenous injections in unrestrained rats

Experimental morphine addiction: method for automatic intravenous injections in unrestrained rats

J R WEEKS. Science..

Abstract

An operant behavioral study on morphine addiction utilized a self-injection technique for giving intravenous injections to relatively unrestrained rats. The rate of self-injection varied inversely with the dose. Morphine was a reinforcer that produced almost immediate satiation.

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