doi: 10.1159/000067108.
Ambient air quality and occurrence of multiple sclerosis relapse
Affiliations
- PMID:12566960
- DOI: 10.1159/000067108
Item in Clipboard
Ambient air quality and occurrence of multiple sclerosis relapse
M Oikonen et al. Neuroepidemiology.2003 Jan-Feb.
Display options
Format
Display options
Format
Abstract
Infectious viruses and bacteria can trigger multiple sclerosis (MS) exacerbations. Seasonally changing concentrations of ambient air pollutants are known to predispose to transmissible infections, to induce systemic immune responses and to enhance existing peripheral inflammation. Ambient air quality and monthly MS relapse occurrence in south-western Finland were compared by multivariate logistic regression. The odds ratio of the risk of a relapse onset was over fourfold (4.143, p < 0.001) when the concentration of inhalable particulate matter (PM(10)) was at the highest quartile. Inhalable airborne particulate matter concentrations were connected to relapse occurrence. Poor air quality may enhance the seasonal changes in MS relapse occurrence by an increased susceptibility to transmissible infections.
Copyright 2003 S. Karger AG, Basel
Similar articles
- Beta-interferon protects multiple sclerosis patients against enhanced susceptibility to infections caused by poor air quality.Oikonen MK, Erälinna JP.Oikonen MK, et al.Neuroepidemiology. 2008;30(1):13-9. doi: 10.1159/000113301. Epub 2008 Jan 17.Neuroepidemiology. 2008.PMID:18204292
- Temporal relationship between environmental influenza A and Epstein-Barr viral infections and high multiple sclerosis relapse occurrence.Oikonen M, Laaksonen M, Aalto V, Ilonen J, Salonen R, Erälinna JP, Panelius M, Salmi A.Oikonen M, et al.Mult Scler. 2011 Jun;17(6):672-80. doi: 10.1177/1352458510394397. Epub 2011 Jan 6.Mult Scler. 2011.PMID:21212088
- Effects of concentrated ambient particles on normal and hypersecretory airways in rats.Harkema JR, Keeler G, Wagner J, Morishita M, Timm E, Hotchkiss J, Marsik F, Dvonch T, Kaminski N, Barr E.Harkema JR, et al.Res Rep Health Eff Inst. 2004 Aug;(120):1-68; discussion 69-79.Res Rep Health Eff Inst. 2004.PMID:15543855
- Respiratory gases, air pollution and epilepsy.Fernandes MJS, Carletti CO, Sierra de Araújo LF, Santos RC, Reis J.Fernandes MJS, et al.Rev Neurol (Paris). 2019 Dec;175(10):604-613. doi: 10.1016/j.neurol.2019.07.013. Epub 2019 Sep 10.Rev Neurol (Paris). 2019.PMID:31519304Review.
- [Small (<2.5 micron) particulate matter concentration of ambient air and early death in Hungary].Losonczy G.Losonczy G.Orv Hetil. 2012 Feb 26;153(8):285-8. doi: 10.1556/OH.2012.29315.Orv Hetil. 2012.PMID:22330839Review.Hungarian.
Cited by
- Examining the contributions of environmental quality to pediatric multiple sclerosis.Lavery AM, Waldman AT, Charles Casper T, Roalstad S, Candee M, Rose J, Belman A, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Ness J, Harris Y, Graves J, Krupp L, Benson L, Gorman M, Moodley M, Rensel M, Goyal M, Mar S, Chitnis T, Schreiner T, Lotze T, Greenberg B, Kahn I, Rubin J, Waubant E; U.S. Network of Pediatric MS Centers.Lavery AM, et al.Mult Scler Relat Disord. 2017 Nov;18:164-169. doi: 10.1016/j.msard.2017.09.004. Epub 2017 Sep 7.Mult Scler Relat Disord. 2017.PMID:29141802Free PMC article.
- Ambient urban dust particulate matter reduces pathologic T cells in the CNS and severity of EAE.O'Driscoll CA, Owens LA, Hoffmann EJ, Gallo ME, Afrazi A, Han M, Fechner JH, Schauer JJ, Bradfield CA, Mezrich JD.O'Driscoll CA, et al.Environ Res. 2019 Jan;168:178-192. doi: 10.1016/j.envres.2018.09.038. Epub 2018 Oct 1.Environ Res. 2019.PMID:30316103Free PMC article.
- Association between Air Pollution and the Development of Rheumatic Disease: A Systematic Review.Sun G, Hazlewood G, Bernatsky S, Kaplan GG, Eksteen B, Barnabe C.Sun G, et al.Int J Rheumatol. 2016;2016:5356307. doi: 10.1155/2016/5356307. Epub 2016 Oct 25.Int J Rheumatol. 2016.PMID:27847517Free PMC article.Review.
- Association between exposure to air pollution and thalamus volume in adults: A cross-sectional study.Hedges DW, Erickson LD, Gale SD, Anderson JE, Brown BL.Hedges DW, et al.PLoS One. 2020 Mar 30;15(3):e0230829. doi: 10.1371/journal.pone.0230829. eCollection 2020.PLoS One. 2020.PMID:32226035Free PMC article.
- The Air We Breathe: Air Pollution as a Prevalent Proinflammatory Stimulus Contributing to Neurodegeneration.Jankowska-Kieltyka M, Roman A, Nalepa I.Jankowska-Kieltyka M, et al.Front Cell Neurosci. 2021 Jun 24;15:647643. doi: 10.3389/fncel.2021.647643. eCollection 2021.Front Cell Neurosci. 2021.PMID:34248501Free PMC article.
Publication types
MeSH terms
Related information
LinkOut - more resources
Full Text Sources
Medical