Review
doi: 10.1038/nature01408.DNA damage and repair
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- PMID:12540918
- DOI: 10.1038/nature01408
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Review
DNA damage and repair
Errol C Friedberg. Nature..
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Abstract
The aesthetic appeal of the DNA double helix initially hindered notions of DNA mutation and repair, which would necessarily interfere with its pristine state. But it has since been recognized that DNA is subject to continuous damage and the cell has an arsenal of ways of responding to such injury. Although mutations or deficiencies in repair can have catastrophic consequences, causing a range of human diseases, mutations are nonetheless fundamental to life and evolution.
Comment in
- DNA replication and recombination.Alberts B.Alberts B.Nature. 2003 Jan 23;421(6921):431-5. doi: 10.1038/nature01407.Nature. 2003.PMID:12540917Review.
Comment on
- The double helix: a personal view.Crick F.Crick F.Nature. 1974 Apr 26;248(5451):766-9. doi: 10.1038/248766a0.Nature. 1974.PMID:4599081No abstract available.
- A structure for deoxyribose nucleic acid. 1953.Watson JD, Crick FH.Watson JD, et al.Nature. 2003 Jan 23;421(6921):397-8; discussion 396.Nature. 2003.PMID:12569935No abstract available.
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