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Case Reports
.2002 Sep;86(9):1064-5.
doi: 10.1136/bjo.86.9.1064.

Acute bilateral blindness caused by accidental methanol intoxication during fire "eating"

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Case Reports

Acute bilateral blindness caused by accidental methanol intoxication during fire "eating"

C Cursiefen et al. Br J Ophthalmol.2002 Sep.
No abstract available

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Figures

Figure 1
Figure 1
Right (A) and left (B) optic discs of the patient with pseudoglaucomatous optic neuropathy secondary to methanol intoxication (optic disc area both eyes: 2.6 mm2; neuroretinal rim area right eye: 1.1 mm2; left eye: 0.92 mm2). Note intensely pale appearance of the optic disc with alteration of neuroretinal rim configuration and (most likely) pre-existing peripapillary atrophy zone. Note also the “washboard-like” pattern of the internal limiting membrane (arrow) secondary to acute loss of retinal nerve fibres.
Figure 2
Figure 2
MRT imaging of the patient with methanol intoxication during fire eating (6 weeks after ingestion). Bilateral symmetric necrotic areas in the basal ganglia (putamen; arrow) in the T1 weighted image (hypointense lesions with marginal contrast enhancement) are typical of methanol intoxication.
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References

    1. Liu JJ, Daya MR, Mann NC. Methanol-related deaths in Ontario. J Toxicol Clin Toxicol 1999;37:69–73. - PubMed
    1. Kuteifan K, Oesterlé, Tajahmady T,et al. Necrosis and haemorrhage of the putamen in methanol poisoning shown on MRI. Neuroradiology 1998;40:158–60. - PubMed
    1. Onder F, Ilker S, Kansu T,et al. Acute blindness and putaminal necrosis in methanol intoxication. Int Ophthalmol 1998;22:81–4. - PubMed
    1. Seme MT, Summerfelt P, Neitz J,et al. Differential recovery of retinal function after mitochondrial inhibition by methanol intoxication. Invest Ophthalmol Vis Sci 2001;42:834–41. - PubMed
    1. Eells J, Henry M, Lewandowski M,et al. Development and characterization of a rodent model of methanol-induced retinal and optic nerve toxicity. Neurotoxicology 2000;21:321–30. - PubMed

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