Comment
doi: 10.1172/JCI15865.The thyroid axis just got more complicated
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- PMID:12045252
- PMCID: PMC151003
- DOI: 10.1172/JCI15865
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Comment
The thyroid axis just got more complicated
Fredric E Wondisford. J Clin Invest.2002 Jun.
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The role of thyrostimulin in the thyroid axis and periphery. Thyrostimulin, a heterodimeric glycoprotein hormone, is synthesized in the pituitary and other peripheral tissues. It is suggested to act in a paracrine fashion at these sites. A role for thyrostimulin at the thyroid is purely speculative.
Comment on
- Thyrostimulin, a heterodimer of two new human glycoprotein hormone subunits, activates the thyroid-stimulating hormone receptor.Nakabayashi K, Matsumi H, Bhalla A, Bae J, Mosselman S, Hsu SY, Hsueh AJ.Nakabayashi K, et al.J Clin Invest. 2002 Jun;109(11):1445-52. doi: 10.1172/JCI14340.J Clin Invest. 2002.PMID:12045258Free PMC article.
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References
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- Hsu, S.Y., Nakabayashi, K., and Bhalla, A. 2002. Evolution of glycoprotein hormone subunit genes in bilateral metazoa: identification of two novel human glycoprotein hormone subunit family genes, GPA2 and GPB5. Mol. Endocrinol. In press. - PubMed
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